Protein Alignment Fatp2 and ACSL1

DIOPT Version :9

• Sequence 1: NP_995925.2
• Gene: Fatp2 / 37657
• FlyBaseID: FBgn0265187
• Length: 714
• Species: Drosophila melanogaster
• Sequence 2: NP_001273637.1
• Gene: ACSL1 / 2180
• HGNCID: 3569
• Length: 698
• Species: Homo sapiens
• Alignment Length: 697
• Identity: 143/697 - (20%)
• Similarity: 224/697 - (32%)
• Gaps: 258/697 - (37%)

  Fly   150 ARQPDKLAIVSESQQW-TFRQVNEHSNRVANVFHSHGYKKG--DVVGLLLENRAEFVATWLGLSK 211
            :|:||      :..:| :::||.|.|..:.:.....|:|..  ..:|:..:||.|:|....|...
Human   111 SRKPD------QPYEWLSYKQVAELSECIGSALIQKGFKTAPDQFIGIFAQNRPEWVIIEQGCFA 169

  Fly   212 IG-VITPLINTNLRGASLQHSITVGQCTALIYGASFRSAVMDIAKDLPAHVGLYQFNDESN---- 271
            .. ||.||.:| |...::.:.:...:.:.:..             |.|....|.....|:.
Human   170 YSMVIVPLYDT-LGNEAITYIVNKAELSLVFV-------------DKPEKAKLLLEGVENKLIPG 220

  Fly   272 ------QEVVASEGLSQGLAQQLNGLLETAAKDKVAAGASRADH--------HDKLVYIYTSGTT 322
                  .:...||.:.:|   |..|:..|:.|.....|  ||:.        .|..|..:|||||
Human   221 LKIIVVMDAYGSELVERG---QRCGVEVTSMKAMEDLG--RANRRKPKPPAPEDLAVICFTSGTT 280

  Fly   323 GLPKAAVITHSRYF-----FIAAGIHYTLGFKDQDVFYTPLPLYHTAGGVMSMGQALLFGSTVVI 382
            |.||.|::||....     |:.| ...|:.....|...:.|||.|....|:.. ..|..|:.:
Human   281 GNPKGAMVTHRNIVSDCSAFVKA-TENTVNPCPDDTLISFLPLAHMFERVVEC-VMLCHGAKI-- 341

  Fly   383 RKKFSASGYF--------SDCARFQCTV----------------GQYIGEMARYILATPSAPHD- 422
                   |:|        .|....|.||                ||....:.|::|...|...:
Human   342 -------GFFQGDIRLLMDDLKVLQPTVFPVVPRLLNRMFDRIFGQANTTLKRWLLDFASKRKEA 399

  Fly   423 -------RN---------HQVR---------MVFGNG---------LRPQIWPQFVERFGIRKVG 453
                   ||         |:|:         ||.|..         ||..:..||.|.
Human   400 ELRSGIIRNNSLWDRLIFHKVQSSLGGRVRLMVTGAAPVSATVLTFLRAALGCQFYEG------- 457

  Fly   454 EFYGATEGNAN---IMNNDSTVGAIGFISRILPQIYPISIIKADPHTGEPLRNSQGLCERCEADE 515
              ||.||..|.   .|..|.|.|.:|     .|.  |.::||...........::|..|.|
Human   458 --YGQTECTAGCCLTMPGDWTAGHVG-----APM--PCNLIKLVDVEEMNYMAAEGEGEVC---- 509

  Fly   516 PGVFVGKIVRGNPCREFLGYVDQKASSKKVVHDVFSKGDMAFISGDLLVADERGYLYFKDRTGDT 580
                    |:|.  ..|.||:...|.:.:.:                   |:.|:|:    |||.
Human   510 --------VKGP--NVFQGYLKDPAKTAEAL-------------------DKDGWLH----TGDI 541

  Fly   581 FRW-------------------KGENVSTSEVEAQLSNLAGYKDVIVYGVSIPNTEGRAGMAAIY 626
            .:|                   :||.::..::|...........|.|:|.|:     :|.:.||.
Human   542 GKWLPNGTLKIIDRKKHIFKLAQGEYIAPEKIENIYMRSEPVAQVFVHGESL-----QAFLIAIV 601

  Fly   627 DPTREV-----------------------------NVSQLG-------VELAKSLPNYARPQFLR 655
            .|..|.                             ::.:||       .|..|.:.  ..|:
Human   602 VPDVETLCSWAQKRGFEGSFEELCRNKDVKKAILEDMVRLGKDSGLKPFEQVKGIT--LHPE--- 661

  Fly   656 FLRKID---LTGTFKLRKVELQQQGFNPEIIDDELFYAQPDGVYAPL 699
             |..||   ||.|.|.::.||:           ..|.:|.|.:|:.:
Human   662 -LFSIDNGLLTPTMKAKRPELR-----------NYFRSQIDDLYSTI 696

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fatp2	NP_995925.2	PRK08279	115..714	CDD:236217	143/697 (21%)
		AFD_class_I	163..680	CDD:302604	136/663 (21%)
ACSL1	NP_001273637.1	LC-FACS_euk	116..694	CDD:341250	139/682 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165149028
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.930