DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Fatp2 and Acsl6

DIOPT Version :9

Sequence 1:	NP_995925.2	Gene:	Fatp2 / 37657	FlyBaseID:	FBgn0265187	Length:	714	Species:	Drosophila melanogaster
Sequence 2:	XP_030101662.1	Gene:	Acsl6 / 216739	MGIID:	894291	Length:	748	Species:	Mus musculus

Alignment Length:	707	Identity:	143/707 - (20%)
Similarity:	235/707 - (33%)	Gaps:	254/707 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly   151 RQPDKLAIVSESQQW-TFRQVNEHSNRVANVFHSHGYKKG--DVVGLLLENRAEFVATWLGLSKI 212
            |:|:      :..|| ::::|.:.:..:.:....|..|.|  ..||:..:||.|::...|.....
Mouse   137 RKPE------QPYQWLSYQEVAKRAEFLGSGLLQHDCKVGTEQFVGVFAQNRPEWIIAELACYTY 195

  Fly   213 G-VITPLINTNLRGASLQHSI-TVGQCTALIYGASFRSAVMDIAKDLPAHVGLYQFNDESNQE-- 273
            . |:.||.:| |...|:.:.| |...||.::              |.|....|...:.|..:.
Mouse   196 SMVVVPLYDT-LGPGSISYIINTADICTVIV--------------DKPHKATLLLEHVERKETPG 245

  Fly   274 ---VVASEGLSQGLAQQLNGLLETAAKDKVAAGASRADHH--------DKLVYIYTSGTTGLPKA 327
               |:..|.....|.::...........:......|.:||        |..:..:||||||.||.
Mouse   246 LKLVILMEPFEDALRERGKKCGVDIKSMQAIEDCGRENHHAPVPPRPDDLSIVCFTSGTTGNPKG 310

  Fly   328 AVITHSRYFFIAAGIHYTLGF----------KDQDVFYTPLPLYHTAGGVMSMGQALLFGSTVVI 382
            |::||..   :.|...   ||          :..||..:.|||.|            :|..  ||
Mouse   311 AMLTHGN---VVADFS---GFLKVTEKVIFPRQDDVLISFLPLAH------------MFER--VI 355

  Fly   383 RKKFS---ASGYFSDCARFQCTVGQYIGEMARYILATPSAPHDRNHQVRMVFGNG---------- 434
            :.:::   |..:||     ...:......|.:.::..        |..|:.|..|
Mouse   356 QSQWAPTCADVHFS-----YLPLAHMFERMVQSVVYC--------HGGRVGFFQGDIRLLSDDMK 407

  Fly   435 -LRPQIWPQFVERFGIRKVGE-FYGA-----------------TEGNANIMNNDS---------- 470
             |||.|:| .|.|...|...: |:.|                 .|..:.|:.|:|
Mouse   408 ALRPTIFP-VVPRLLNRMYDKIFHQADTSLKRWLLEFAAKRKQAEVRSGIIRNNSIWDELFFNKI 471

  Fly   471 --TVGAIGFISRILPQIYPISIIKADPHTGEPLRNSQGLCE------------RCEADEPGVFV- 520
              ::|  |.:..|:....|     |.|.....||.:.| |:            .|....||.:.
Mouse   472 QASLG--GHVRMIVTGAAP-----ASPTVLGFLRAALG-CQVYEGYGQTECTAGCTFTTPGDWTS 528

  Fly   521 GKIVRGNPCR-------EFLGYVDQKASSKKVVHDVFSKGDMAFISGDLLVADERGYLYFKDR-- 576
            |.:....||.       |.|.|...|...     ::..||...|          :|||..:||
Mouse   529 GHVGAPLPCNHIKLVDAEELNYWTCKGEG-----EICVKGPNVF----------KGYLKDEDRTK 578

  Fly   577 ----------TGDTFRW-------------------KGENVSTSEVEAQLSNLAGYKDVIVYGVS 612
                      |||..:|                   :||.|:..::|...........:.|:|.|
Mouse   579 EALDSDGWLHTGDIGKWLPEGTLKIIDRKKHIFKLAQGEYVAPEKIENIYIRSEPVAQIYVHGDS 643

  Fly   613 IPNTEGRAGMAAIYDPTREVNVSQLGVELAKSLPNYARPQFLRFLRKIDLTGTFK--LRKVELQQ 675
            :     :|.:..|..|..||            :|::|        :|..:.||::  ..|.||::
Mouse   644 L-----KAFLVGIVVPDPEV------------MPSWA--------QKKGIEGTYQELCMKKELKK 683

  Fly   676 QGFNPEIIDDELFYAQPDGVYA-------------------PLTPSVYERIVRNELR 713
                 .|:||.:...:..|:::                   .|||::  :..|.|||
Mouse   684 -----AILDDMVMLGKESGLHSFEQVKAIYIHCDMFSVQNGLLTPTL--KAKRPELR 733

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fatp2	NP_995925.2	PRK08279	115..714	CDD:236217	143/707 (20%)
Fatp2	NP_995925.2	AFD_class_I	163..680	CDD:302604	130/641 (20%)
Acsl6	XP_030101662.1	LC-FACS_euk	141..744	CDD:341250	141/697 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167839095
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930