DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Fatp2 and Acsbg1

DIOPT Version :9

Sequence 1:	NP_995925.2	Gene:	Fatp2 / 37657	FlyBaseID:	FBgn0265187	Length:	714	Species:	Drosophila melanogaster
Sequence 2:	NP_599216.1	Gene:	Acsbg1 / 171410	RGDID:	708557	Length:	721	Species:	Rattus norvegicus

Alignment Length:	695	Identity:	139/695 - (20%)
Similarity:	237/695 - (34%)	Gaps:	252/695 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly   151 RQPDKLAIVSESQQWTFRQVNEHSNRVANVFHSHGYKKGDVVGLLLENRAEFVATWLGLSKIGVI 215
            ::.||...:|..|.:..      :.:||..|...|.::...|.:|..|..|:..:.:|....|.|
  Rat   122 KRKDKWERISYYQYYLI------ARKVAKGFLKLGLERAHSVAILGFNSPEWFFSAVGTVFAGGI 180

  Fly   216 TPLINTNLRGASLQHSITVGQCTALIYGASFR---SAVMDIAKDLPAH---VGLYQ-------FN 267
            ...|.|.....:.|:  ....|.|.:.....:   ..::.|.|||| |   |.:||       .|
  Rat   181 VTGIYTTSSPEACQY--IAHDCRANVIVVDTQKQLEKILKIWKDLP-HLKAVVIYQEPPPKKMAN 242

  Fly   268 DESNQEVVASEGLSQGLAQQ-LNGLLETAAKDKVAAGASRADHHDKLVYIYTSGTTGLPKAAVIT 331
            ..:.:|::.   |.|.:.:: |:.:::|...::..            |.:|||||||.||..:::
  Rat   243 VYTMEELIE---LGQEVPEEALDAIIDTQQPNQCC------------VLVYTSGTTGNPKGVMLS 292

  Fly   332 H------SRYFFIAAGIHYTLGFKDQDVFYTPLPLYHTAGGVMSMGQALLFGSTVVIRKKFSASG 390
            .      :||...|..|.  .....|:|..:.|||.|.|..:..:...:.:|:.|.
  Rat   293 QDNITWTARYGSQAGDIQ--PAEVQQEVVVSYLPLSHIAAQIYDLWTGIQWGAQVC--------- 346

  Fly   391 YFSDCARFQCTVGQYIGEMARYILATPSAPHDRNHQVRMVFGNGLRPQIWPQFVERFGIRKVGEF 455
             |:|....:.|:...:.|:           ...:|.       |: |::|.:.:||  |::|...
  Rat   347 -FADPDALKGTLVNTLREV-----------EPTSHM-------GV-PRVWEKIMER--IQEVAAQ 389

  Fly   456 YG-------------ATEGNANIMNND-----STVG----------AIGFISRILPQIYPISIIK 492
            .|             ..|.|....:||     |.:.          |:|| ::.....|     .
  Rat   390 SGFIRRKMLLWAMSVTLEQNLTCPSNDLKPFTSRLADYLVLARVRQALGF-AKCQKNFY-----G 448

  Fly   493 ADPHTGEPLRNSQGLCER-------CEADEPGVF----------VGKIVRGNPCRE--------- 531
            |.|.|.|..|...||..|       .|:..|...          .|::|.|  ||.
  Rat   449 AAPMTAETQRFFLGLNIRLYAGYGLSESTGPHFMSSPYNYRLYSSGRVVPG--CRVKLVNQDADG 511

  Fly   532 -----------FLGYVDQKASSKKVVHDVFSKGDMAFISGDLLVADERGYLYFKDRTGD-TFRWK 584
                       |:||::.:..:.:.:.   |:|.:.  :||:...|:.|:||...|..: .....
  Rat   512 IGEICLWGRTIFMGYLNMEDKTHEAID---SEGWLH--TGDMGRLDDDGFLYITGRLKELIITAG 571

  Fly   585 GENV-----------------------------------------STSE---------VE----- 594
            ||||                                         .|||         ||
  Rat   572 GENVPPVPIEEAVKMELPIISSAMLIGDQRKFLSMLLTLKCTLNPETSEPTDNLTEQAVEFCQRV 636

  Fly   595 ----AQLSNLAGYKDVIVYGVSIPNTEGRAGMAAIYDPTREVNVSQLGVELAKSLPNYARPQFLR 655
                :.:|.:.|.||..||             .||::..:.||.:..           |||..::
  Rat   637 GSKASTVSEIVGQKDEAVY-------------QAIHEGIQRVNANAA-----------ARPYHIQ 677

  Fly   656 ----FLRKIDLTG-----TFKLRKVELQQQGFNPEIIDDELFYAQ 691
                ..|...::|     |.||:::.:.::  ..:|||.  ||.:
  Rat   678 KWAILERDFSISGGELGPTMKLKRLTVLEK--YKDIIDS--FYQE 718

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fatp2	NP_995925.2	PRK08279	115..714	CDD:236217	139/695 (20%)
Fatp2	NP_995925.2	AFD_class_I	163..680	CDD:302604	131/670 (20%)
Acsbg1	NP_599216.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..64
Acsbg1	NP_599216.1	ACSBG_like	122..716	CDD:341256	137/691 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166342855
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930