Protein Alignment Fatp2 and SLC27A2

DIOPT Version :10

• Sequence 1: NP_995925.2
• Gene: Fatp2 / 37657
• FlyBaseID: FBgn0265187
• Length: 714
• Species: Drosophila melanogaster
• Sequence 2: NP_003636.2
• Gene: SLC27A2 / 11001
• HGNCID: 10996
• Length: 620
• Species: Homo sapiens
• Alignment Length: 662
• Identity: 244/662 - (36%)
• Similarity: 353/662 - (53%)
• Gaps: 56/662 - (8%)

  Fly    65 ILAPVLTAISGLILYYQGPWYGVATLYAALISILLVRPGWRWFY--------IAAVTTPRDTVAL 121
            :|:.:.|.::||                 |...|||.....:|:        :|||..
Human     1 MLSAIYTVLAGL-----------------LFLPLLVNLCCPYFFQDIGYFLKVAAVGR------- 41

  Fly   122 FAYIRVLLFIKRQERKNLNIGDIFESNVARQPDKLAIVSESQQWTFRQVNEHSNRVANVFHSH-G 185
                ||..:.||:..:  .|...|.....:.|.|..::...:..|:.||:..||:||...|.| |
Human    42 ----RVRSYGKRRPAR--TILRAFLEKARQTPHKPFLLFRDETLTYAQVDRRSNQVARALHDHLG 100

  Fly   186 YKKGDVVGLLLENRAEFVATWLGLSKIGVITPLINTNLRGASLQHSITVGQCTALIYGASFRSAV 250
            .::||.|.||:.|...:|..||||.|:|.....:|.|:|..||.|.........|:.....::||
Human   101 LRQGDCVALLMGNEPAYVWLWLGLVKLGCAMACLNYNIRAKSLLHCFQCCGAKVLLVSPELQAAV 165

  Fly   251 MDIAKDLPA-HVGLYQFNDESNQEVVASEGLSQGLAQQLNGLLETAAKDKVAAGASRADHHDKLV 314
            .:|...|.. .|.:|..:..||         :.|:...|:.:.|.:.:....:..|........:
Human   166 EEILPSLKKDDVSIYYVSRTSN---------TDGIDSFLDKVDEVSTEPIPESWRSEVTFSTPAL 221

  Fly   315 YIYTSGTTGLPKAAVITHSRYFFIAAGIHYTLGFKDQDVFYTPLPLYHTAGGVMSMGQALLFGST 379
            ||||||||||||||:|||.|.:: ..|:.:..|.|..||.|..||.||:|..::.:...::.|:|
Human   222 YIYTSGTTGLPKAAMITHQRIWY-GTGLTFVSGLKADDVIYITLPFYHSAALLIGIHGCIVAGAT 285

  Fly   380 VVIRKKFSASGYFSDCARFQCTVGQYIGEMARYILATPSAPHDRNHQVRMVFGNGLRPQIWPQFV 444
            :.:|.|||||.::.||.::..||.|||||:.||:..:|..|:||:|:||:..|||||..:|.|||
Human   286 LALRTKFSASQFWDDCRKYNVTVIQYIGELLRYLCNSPQKPNDRDHKVRLALGNGLRGDVWRQFV 350

  Fly   445 ERFGIRKVGEFYGATEGNANIMNNDSTVGAIGFISRILPQIYPISIIKADPHTGEPLRNSQGLCE 509
            :|||...:.|||.|||||...||....|||:|.::.:..:|....:||.|....||:|:..|.|.
Human   351 KRFGDICIYEFYAATEGNIGFMNYARKVGAVGRVNYLQKKIITYDLIKYDVEKDEPVRDENGYCV 415

  Fly   510 RCEADEPGVFVGKIVRGNPCREFLGYVDQKA-SSKKVVHDVFSKGDMAFISGDLLVADERGYLYF 573
            |....|.|:.|.||.:..|   |.||...|| :.||.:.|||.|||:.|.|||||:.|...::||
Human   416 RVPKGEVGLLVCKITQLTP---FNGYAGAKAQTEKKKLRDVFKKGDLYFNSGDLLMVDHENFIYF 477

  Fly   574 KDRTGDTFRWKGENVSTSEVEAQLSNLAGYKDVIVYGVSIPNTEGRAGMAAI-YDPTREVNVSQL 637
            .||.|||||||||||:|:||...:..:...::|.||||.:|:.|||.|||:| .....|.:..:|
Human   478 HDRVGDTFRWKGENVATTEVADTVGLVDFVQEVNVYGVHVPDHEGRIGMASIKMKENHEFDGKKL 542

  Fly   638 GVELAKSLPNYARPQFLRFLRKIDLTGTFKLRKVELQQQGFNPEIIDDELFYAQPDG-VYAPLTP 701
            ...:|..||:||||:|||....|::|||||.||:.|.::||||.:|.|.|::..... :|.|:|.
Human   543 FQHIADYLPSYARPRFLRIQDTIEITGTFKHRKMTLVEEGFNPAVIKDALYFLDDTAKMYVPMTE 607

  Fly   702 SVYERIVRNELR 713
            .:|..|....|:
Human   608 DIYNAISAKTLK 619

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fatp2	NP_995925.2	Adenylate forming domain, Class I superfamily	163..680	CDD:473059	213/520 (41%)
SLC27A2	NP_003636.2	hsFATP2a_ACSVL_like	74..610	CDD:341261	221/548 (40%)