DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Fatp2 and slc27a4

DIOPT Version :9

Sequence 1:	NP_995925.2	Gene:	Fatp2 / 37657	FlyBaseID:	FBgn0265187	Length:	714	Species:	Drosophila melanogaster
Sequence 2:	XP_004914245.1	Gene:	slc27a4 / 101735131	XenbaseID:	XB-GENE-957679	Length:	643	Species:	Xenopus tropicalis

Alignment Length:	628	Identity:	298/628 - (47%)
Similarity:	405/628 - (64%)	Gaps:	15/628 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    83 PWYGVATLYAALISILLVRPGWRWFYIAAVTTPRDTVALFAYIRVLLFIKRQERKNLNIGDIFES 147
            ||:   ....|::...|...||::..:..:|..||.......:||.|.:::..|:...|.|||:.
Frog    21 PWF---QSIGAVLVFYLGSGGWKFMRVFCMTISRDLWGALTLVRVKLQVRKHLRERNTIPDIFKE 82

  Fly   148 NVARQPDKLAIVSE--SQQWTFRQVNEHSNRVANVFHSHGYKKGDVVGLLLENRAEFVATWLGLS 210
            .|.|.|:|.|::.|  ...|||.:::|.||.|||..|:.|::.|||:.|.:||..|:|..|||::
Frog    83 CVKRHPNKTALIFEGTGASWTFMELDEFSNAVANFLHAEGFRSGDVIALFMENCNEYVGLWLGMA 147

  Fly   211 KIGVITPLINTNLRGASLQHSITVGQCTALIYGASFRSAVMDIAKDLPAHVGLYQFNDESNQEVV 275
            ||||...|||.|||..:|:|..||....|:|:|.....|:.|:...:...|.||.|.:...:.|.
Frog   148 KIGVEAALINFNLRLDALEHCFTVSNSKAVIFGKEMSQAMCDVHSLMGKSVRLYCFGECDPKTVP 212

  Fly   276 ASEGLSQGLAQQLNGLLETAAKDKVAAGASRADHHDKLVYIYTSGTTGLPKAAVITHSRYFFIAA 340
            ..       |:.|:.||::|::.. ..|..|: ..|||.||||||||||||||::.|||||.:||
Frog   213 VG-------AEFLDSLLQSASRHP-PKGPGRS-FTDKLFYIYTSGTTGLPKAAIVVHSRYFRMAA 268

  Fly   341 GIHYTLGFKDQDVFYTPLPLYHTAGGVMSMGQALLFGSTVVIRKKFSASGYFSDCARFQCTVGQY 405
            .:||..|.:..||.|..|||||:||.::.:||.||.|.||||:||||||.::.|||::.||:.||
Frog   269 LVHYGFGMRSDDVVYDCLPLYHSAGNIVGIGQCLLHGLTVVIKKKFSASRFWDDCAKYNCTIVQY 333

  Fly   406 IGEMARYILATPSAPHDRNHQVRMVFGNGLRPQIWPQFVERFGIRKVGEFYGATEGNANIMNNDS 470
            |||:.||:|..|....:..|:|||..||||||.||.:|..||.|.:|.|||||||.|.::.|.|:
Frog   334 IGEICRYLLNQPVREAESQHRVRMALGNGLRPAIWTEFTSRFRIPQVAEFYGATECNCSLGNFDN 398

  Fly   471 TVGAIGFISRILPQIYPISIIKADPHTGEPLRNSQGLCERCEADEPGVFVGKIVRGNPCREFLGY 535
            .|||.||.|||||.:|||.::|.:..|.|.:|::||||..|...|||..||:|::.:|.|.|.||
Frog   399 HVGACGFNSRILPFVYPIRLMKVNEDTMELIRDAQGLCIPCRPGEPGQLVGRIIQSDPLRRFDGY 463

  Fly   536 VDQKASSKKVVHDVFSKGDMAFISGDLLVADERGYLYFKDRTGDTFRWKGENVSTSEVEAQLSNL 600
            |::.|:|||:..|||..||||:::||:||.||.||:||:||||||||||||||||:|||..||.|
Frog   464 VNETATSKKIAKDVFKNGDMAYLTGDVLVMDELGYMYFRDRTGDTFRWKGENVSTTEVEGTLSRL 528

  Fly   601 AGYKDVIVYGVSIPNTEGRAGMAAIYDPTREVNVSQLGVELAKSLPNYARPQFLRFLRKIDLTGT 665
            .|..||:||||.||.|||||||||:.||....::.:...:|.||||.||.|.|||.|.:::.|||
Frog   529 LGQADVVVYGVEIPGTEGRAGMAAVADPNSTCDLEKFAKDLKKSLPAYAHPVFLRILPEVNKTGT 593

  Fly   666 FKLRKVELQQQGFNPEIIDDELFYA-QPDGVYAPLTPSVYERI 707
            :|.:|.|::::.|||.::.|.|:.. ...|.|.|||..||.||
Frog   594 YKFQKTEMRKESFNPHLVKDALYVLDSQQGRYTPLTHDVYSRI 636

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fatp2	NP_995925.2	PRK08279	115..714	CDD:236217	291/596 (49%)
Fatp2	NP_995925.2	AFD_class_I	163..680	CDD:302604	262/516 (51%)
slc27a4	XP_004914245.1	hsFATP4_like	99..608	CDD:341262	262/517 (51%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H68437
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG63225
OrthoDB	1	1.010	-	-		D298283at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR43107
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	6.030