DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Fatp2 and acsbg1

DIOPT Version :9

Sequence 1:	NP_995925.2	Gene:	Fatp2 / 37657	FlyBaseID:	FBgn0265187	Length:	714	Species:	Drosophila melanogaster
Sequence 2:	XP_001344904.2	Gene:	acsbg1 / 100006023	ZFINID:	ZDB-GENE-110914-219	Length:	674	Species:	Danio rerio

Alignment Length:	729	Identity:	143/729 - (19%)
Similarity:	249/729 - (34%)	Gaps:	241/729 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   141 IGD-IFESNVARQPDKLAIVSESQQ-WTFR-------QVNEHSNR----VANVFHSHGYKKGDVV 192
            :|| :.|.||..:....|.::.:|. ||..       :::||...    |..:|::...|.|::.
Zfish     9 VGDGLLEKNVIEEVLACAKLAPAQSLWTTEASGSVQLRMDEHCPEQPITVHQMFYNSVQKYGNLT 73

  Fly   193 GLLLE-----NRAEFVATW------------LGLSKI-GVITPLINTNLRGASLQHSITVGQCTA 239
            .|..:     .:|.|:..:            |||.:. ||.....|:.....:...::..|...|
Zfish    74 ALASKRGNKWEKATFLEYYHLCRMAAKGFLKLGLEQFHGVAILGFNSAEWFIAAVGTVFAGGIMA 138

  Fly   240 LIYGASFRSAVMDIAKDLPAHVGLYQFNDESNQEVVASEGLS--QGLAQQLNGLLETAA-----K 297
            .||..:...|.:.:|.|..|:|.:.:...:.::.:...:.|.  :.:.|....|.|..|     :
Zfish   139 GIYTTNSPDACLHVANDSRANVIVVENQKQLDKIMQVKDKLPHLKAIVQYSGSLKEKLANLYSWE 203

  Fly   298 DKVAAGASRADHH-DKL----------VYIYTSGTTGLPKAAVITHSRYFFIAAGIHYTLGFKD- 350
            :.:..|...:||. |::          |.||||||||.||..:::|....:.|   |:.....|
Zfish   204 EFMELGLEVSDHELDEVISKQRANQCCVLIYTSGTTGSPKGVMLSHDNITWTA---HHASRAGDM 265

  Fly   351 ------QDVFYTPLPLYHTAGGVMSMGQALLFGSTVVIRKKFSASGYFSDCARFQCTVGQYIGEM 409
                  |:...:.|||.|.|..:..:...:.:|..:...:..:..|...|..|
Zfish   266 QPAEIRQESLVSYLPLSHIAAQIYDLWTGIKWGEQISFAQPDALKGTLVDSLR------------ 318

  Fly   410 ARYILATPSAPHDRNHQVRMVFGNGLRPQIWPQFVERF--GIRKVG---------EFYGATEGNA 463
                ..||:|     |.       |: |::|.:.:|:.  ||.:.|         ....:.:.|.
Zfish   319 ----EVTPTA-----HM-------GV-PRVWEKIMEKIKEGISRCGYMKRKMVTWAMSVSLDANQ 366

  Fly   464 NIMNNDS-----TVGAIGFISRILPQIYPISIIK----ADPHTGEPLRNSQGLCER-------CE 512
            .:..::.     |:.....:.::..::...|.:|    |.|...|.|:...||..|       .|
Zfish   367 RLKKDEEKSFLFTLAEKLILQKLRAELGFSSCVKFFSGAAPIGRETLQFFLGLNIRLYEAYGMSE 431

  Fly   513 ADEPG----------VFVGKIV--------------RGNPC----REFLGYVDQKASSKKVVHDV 549
            ...|.          :..||:|              .|..|    ..|:|:::.:..:|:.:.:
Zfish   432 TSGPHFMSGPEAYQFLSCGKVVPGCQYKLININADGSGEVCFWGRNVFMGFLNLEDKTKEALDE- 495

  Fly   550 FSKGDMAFISGDLLVADERGYLYFKDRTGD-TFRWKGENVSTSEVE------------------- 594
                |....||||...||.|::|...|..: .....|||:....:|
Zfish   496 ----DGWLRSGDLGKVDEDGFIYINGRIKELIITAGGENIPPLPIEDAVKQELSIISNAMLIGDE 556

  Fly   595 ----------------------------------------AQLSNLAGYKDVIVYGVSIPNTEGR 619
                                                    .:||::.|.||.:||
Zfish   557 RKFLSMLLTLKCTVNPETTEPTDILSLEAVEFCQRIGSQSTKLSDITGGKDKLVY---------- 611

  Fly   620 AGMAAIYDPTREVNVSQLGVELAKSLPNYARPQFLRFLRKI------DLTGTFKLRK-VELQQQG 677
               .:|.|...:||        :|:..|..|.|....|.|.      :|..|.|||: |.||.
Zfish   612 ---KSIEDGIGQVN--------SKATSNAQRIQKWTILDKDFSVAGGELGPTMKLRRPVVLQM-- 663

  Fly   678 FNPEIIDDELFYAQ 691
            ::.||   |.||.:
Zfish   664 YHNEI---ENFYRE 674

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fatp2	NP_995925.2	PRK08279	115..714	CDD:236217	143/729 (20%)
Fatp2	NP_995925.2	AFD_class_I	163..680	CDD:302604	132/693 (19%)
acsbg1	XP_001344904.2	FAA1	60..674	CDD:223953	131/676 (19%)
acsbg1	XP_001344904.2	ACSBG_like	78..672	CDD:213299	125/656 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170582970
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930