Protein Alignment twi and bhlhe22

DIOPT Version :10

• Sequence 1: NP_523816.2
• Gene: twi / 37655
• FlyBaseID: FBgn0003900
• Length: 490
• Species: Drosophila melanogaster
• Sequence 2: NP_001072933.1
• Gene: bhlhe22 / 780395
• XenbaseID: XB-GENE-6457792
• Length: 296
• Species: Xenopus tropicalis
• Alignment Length: 267
• Identity: 71/267 - (26%)
• Similarity: 105/267 - (39%)
• Gaps: 73/267 - (27%)

  Fly   249 QQLQQQQPHQQSHAQMHFQNAYRQSFEGYEPANSL----------NGSAYSSSDRDDMEYARHNA 303
            |.|...||..:|  .:|       .::|.:|::.|          :|:..::...:.:..|..|.
 Frog    32 QGLDLSQPGDRS--PLH-------CYDGPDPSDLLRHHQHHHQASSGALGAAGANEALALAAANM 87

  Fly   304 LS---------SVSDLNGG-VMSPACLADDGS----------------AGSLLDGSDAGGKAFRK 342
            .:         ||::.:|| ..||    ||.|                ||..:|...|.|..
 Frog    88 CAKFGESAGRVSVAESSGGEEQSP----DDDSDGRCELVLRSAEHRAQAGLKVDAPCATGGG--- 145

  Fly   343 PRRRLKRKPSKTEETDEFSNQRVMANVRERQRTQSLNDAFKSLQQIIPTLPSD---KLSKIQTLK 404
                   |.||.:.|     .|:..|.|||:|...||||...|:.:||...|.   |||||.||.
 Frog   146 -------KKSKEQRT-----LRLNINARERRRMHDLNDALDELRAVIPYAHSPSVRKLSKIATLL 198

  Fly   405 LATRYIDFLCRMLSSSDISLLKALEAQGSPSAYGSASSLLSAAANGAEADLKCLRKANGAPIIPP 469
            ||..||     ::.:..:..::.|.|..:.....||:|:.:.||..|.|....|..|.|| ..|.
 Frog   199 LAKNYI-----LMQAQALEEMRRLVAYLNQGQAISAASIPNPAAAAAAAAAVALHPALGA-YEPA 257

  Fly   470 EKLSYLF 476
            ..:.|.|
 Frog   258 AAVGYPF 264

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
twi	NP_523816.2	bHLH_TS_TWIST	363..421	CDD:381470	25/60 (42%)
bhlhe22	NP_001072933.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	26..70		9/46 (20%)
		bHLH_TS_bHLHe22_bHLHb5	154..223	CDD:381524	27/73 (37%)