Sequence 1: | NP_001033967.1 | Gene: | twi / 37655 | FlyBaseID: | FBgn0003900 | Length: | 490 | Species: | Drosophila melanogaster |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_000465.1 | Gene: | TWIST1 / 7291 | HGNCID: | 12428 | Length: | 202 | Species: | Homo sapiens |
Alignment Length: | 281 | Identity: | 85/281 - (30%) |
---|---|---|---|
Similarity: | 117/281 - (41%) | Gaps: | 84/281 - (29%) |
- Green bases have known domain annotations that are detailed below.
Fly 211 VQSTCTSPQSHFDFPDEELPEHKAQVFLPLYNNQQQQSQQLQQQQPHQQSHAQMHFQNAYRQSFE 275
Fly 276 GYEPANSLNGSAYSSSDRDDMEYARHNALSSVSDLNGGVMSPACLADDGSAGSLLDGSDAGGKAF 340
Fly 341 RKPRRRLKRKPSKTEETDEFSNQRVMANVRERQRTQSLNDAFKSLQQIIPTLPSDKLSKIQTLKL 405
Fly 406 ATRYIDFLCRMLSSSDISLLKALEAQGSPSAYGSASSLLSAAANGAEADLKCLRKANGAPIIPPE 470
Fly 471 KLSYLFGVWRMEG----DAQH 487 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
twi | NP_001033967.1 | HLH | 363..413 | CDD:278439 | 43/49 (88%) |
TWIST1 | NP_000465.1 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..105 | 22/147 (15%) | |
HLH | 109..159 | CDD:278439 | 43/49 (88%) | ||
Sufficient for transactivation activity. /evidence=ECO:0000250 | 161..191 | 10/64 (16%) |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 1 | 0.930 | - | - | C165149613 | |
Domainoid | 1 | 1.000 | 90 | 1.000 | Domainoid score | I7783 |
eggNOG | 1 | 0.900 | - | - | E1_KOG4447 | |
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 1 | 0.950 | - | 0 | Normalized mean entropy | S4574 |
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
OrthoFinder | 1 | 1.000 | - | - | FOG0001055 | |
OrthoInspector | 1 | 1.000 | - | - | otm41326 | |
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 1 | 1.100 | - | - | O | PTHR23349 |
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R5507 |
SonicParanoid | 1 | 1.000 | - | - | X1477 | |
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
User_Submission | 0 | 0.000 | Not matched by this tool. | |||
10 | 9.820 |