Protein Alignment twi and Hand2

DIOPT Version :10

• Sequence 1: NP_523816.2
• Gene: twi / 37655
• FlyBaseID: FBgn0003900
• Length: 490
• Species: Drosophila melanogaster
• Sequence 2: NP_073187.1
• Gene: Hand2 / 64637
• RGDID: 621207
• Length: 217
• Species: Rattus norvegicus
• Alignment Length: 181
• Identity: 59/181 - (32%)
• Similarity: 84/181 - (46%)
• Gaps: 44/181 - (24%)

  Fly   256 PHQQSHAQMHFQNAYRQSFEGYEPANSLNGSAYSSSDR---DDMEYARHNALSSVSDLNGGVMSP 317
            ||   |..:|        .|||..|.:...:|.:::.|   ::..|. |..|....:::....|.
  Rat     8 PH---HPVVH--------HEGYPFAAAAAAAAAAAASRCSHEENPYF-HGWLIGHPEMSPPDYSM 60

  Fly   318 ACLAD----DGSAGSLLDGSDAGG-------KAFRKPRRRLKRKPSKTEETDEFSNQRVMANVRE 371
            |....    .|:||  ||.|..||       .....||      |.|         :|..||.:|
  Rat    61 ALSYSPEYASGAAG--LDHSHYGGVPPGAGPPGLGGPR------PVK---------RRGTANRKE 108

  Fly   372 RQRTQSLNDAFKSLQQIIPTLPSD-KLSKIQTLKLATRYIDFLCRMLSSSD 421
            |:||||:|.||..|::.||.:|:| |||||:||:|||.||.:|..:|:..|
  Rat   109 RRRTQSINSAFAELRECIPNVPADTKLSKIKTLRLATSYIAYLMDLLAKDD 159

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
twi	NP_523816.2	bHLH_TS_TWIST	363..421	CDD:381470	31/58 (53%)
Hand2	NP_073187.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	76..116		17/54 (31%)
		bHLH_TS_HAND2	100..161	CDD:381477	32/60 (53%)