DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment twi and Neurog3

DIOPT Version :9

Sequence 1:	NP_001033967.1	Gene:	twi / 37655	FlyBaseID:	FBgn0003900	Length:	490	Species:	Drosophila melanogaster
Sequence 2:	NP_067732.1	Gene:	Neurog3 / 60329	RGDID:	631350	Length:	214	Species:	Rattus norvegicus

Alignment Length:	207	Identity:	58/207 - (28%)
Similarity:	83/207 - (40%)	Gaps:	41/207 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   256 PHQQSHAQMHFQNAYRQSFEGYEPANSLNGSAYSSSDRDDMEYARHNALSSVSDLNGGVMSPACL 320
            ||......:......:|.|.|             :||        |..|||    |....||..:
  Rat     3 PHPLDAPTIQVSQETQQPFPG-------------ASD--------HEVLSS----NSTPPSPTLV 42

  Fly   321 ADDGSAGSLLDGSDAGGKAFRKPRRRLKRKPSKTE--ETDEFSNQRVMANVRERQRTQSLNDAFK 383
            ..|.|..   :..|..|.:.:...||..|...|:|  .:.:..::|..||.|||.|..:||.|..
  Rat    43 PRDCSEA---EAGDCRGTSRKLRARRGGRNRPKSELALSKQRRSRRKKANDRERNRMHNLNSALD 104

  Fly   384 SLQQIIPTLPSD-KLSKIQTLKLATRYIDFLCRMLSSSDISLL----------KALEAQGSPSAY 437
            :|:.::||.|.| ||:||:||:.|..||..|.:.|..:|.|..          ......||...:
  Rat   105 ALRGVLPTFPDDAKLTKIETLRFAHNYIWALTQTLRIADHSFYGPEPPVPCGELGSPGGGSSGDW 169

  Fly   438 GSASSLLSAAAN 449
            ||..|.:|.|.:
  Rat   170 GSIYSPVSQAGS 181

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
twi	NP_001033967.1	HLH	363..413	CDD:278439	24/50 (48%)
Neurog3	NP_067732.1	bHLH_TS_NGN3_ATOH5	77..144	CDD:381561	26/66 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910