Protein Alignment twi and Neurog3

DIOPT Version :10

• Sequence 1: NP_523816.2
• Gene: twi / 37655
• FlyBaseID: FBgn0003900
• Length: 490
• Species: Drosophila melanogaster
• Sequence 2: NP_067732.1
• Gene: Neurog3 / 60329
• RGDID: 631350
• Length: 214
• Species: Rattus norvegicus
• Alignment Length: 207
• Identity: 58/207 - (28%)
• Similarity: 83/207 - (40%)
• Gaps: 41/207 - (19%)

  Fly   256 PHQQSHAQMHFQNAYRQSFEGYEPANSLNGSAYSSSDRDDMEYARHNALSSVSDLNGGVMSPACL 320
            ||......:......:|.|.|             :||        |..|||    |....||..:
  Rat     3 PHPLDAPTIQVSQETQQPFPG-------------ASD--------HEVLSS----NSTPPSPTLV 42

  Fly   321 ADDGSAGSLLDGSDAGGKAFRKPRRRLKRKPSKTE--ETDEFSNQRVMANVRERQRTQSLNDAFK 383
            ..|.|..   :..|..|.:.:...||..|...|:|  .:.:..::|..||.|||.|..:||.|..
  Rat    43 PRDCSEA---EAGDCRGTSRKLRARRGGRNRPKSELALSKQRRSRRKKANDRERNRMHNLNSALD 104

  Fly   384 SLQQIIPTLPSD-KLSKIQTLKLATRYIDFLCRMLSSSDISLL----------KALEAQGSPSAY 437
            :|:.::||.|.| ||:||:||:.|..||..|.:.|..:|.|..          ......||...:
  Rat   105 ALRGVLPTFPDDAKLTKIETLRFAHNYIWALTQTLRIADHSFYGPEPPVPCGELGSPGGGSSGDW 169

  Fly   438 GSASSLLSAAAN 449
            ||..|.:|.|.:
  Rat   170 GSIYSPVSQAGS 181

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
twi	NP_523816.2	bHLH_TS_TWIST	363..421	CDD:381470	26/58 (45%)
Neurog3	NP_067732.1	bHLH_TS_NGN3_ATOH5	77..144	CDD:381561	26/66 (39%)