Protein Alignment twi and Twist2

DIOPT Version :9

• Sequence 1: NP_001033967.1
• Gene: twi / 37655
• FlyBaseID: FBgn0003900
• Length: 490
• Species: Drosophila melanogaster
• Sequence 2: NP_067723.1
• Gene: Twist2 / 59327
• RGDID: 621286
• Length: 160
• Species: Rattus norvegicus
• Alignment Length: 213
• Identity: 74/213 - (34%)
• Similarity: 98/213 - (46%)
• Gaps: 67/213 - (31%)

  Fly   279 PANSLNGSAYSSSDRDDMEYARHNALSSVSDLNGGVMSPACLADDGSAGSLLDGSDAGGKAFRKP 343
            |.:|| |::....:|....:.|....|..|            ::|||.               .|
  Rat    11 PVDSL-GTSEEELERQPKRFGRKRRYSKKS------------SEDGSP---------------TP 47

  Fly   344 RRRLKRKPSKTEETDEFSNQRVMANVRERQRTQSLNDAFKSLQQIIPTLPSDKLSKIQTLKLATR 408
            .:|.|:.....:..:|..:||::|||||||||||||:||.:|::|||||||||||||||||||.|
  Rat    48 GKRGKKGSPSAQSFEELQSQRILANVRERQRTQSLNEAFAALRKIIPTLPSDKLSKIQTLKLAAR 112

  Fly   409 YIDFLCRMLSSSDISLLKALEAQGSPSAYGSASSLLSAAANGAEADLKCLRKANGAPIIPPEKLS 473
            |||||.::|.|.::.                                   .|......:..|:||
  Rat   113 YIDFLYQVLQSDEMD-----------------------------------NKMTSCSYVAHERLS 142

  Fly   474 YLFGVWRMEG----DAQH 487
            |.|.||||||    .|.|
  Rat   143 YAFSVWRMEGAWSMSASH 160

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
twi	NP_001033967.1	HLH	363..413	CDD:278439	41/49 (84%)
Twist2	NP_067723.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..63		14/79 (18%)
		bHLH_TS_TWIST2	51..132	CDD:381543	48/115 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166343491
Domainoid	1	1.000	90	1.000	Domainoid score	I7605
eggNOG	1	0.900	-	-		E1_KOG4447
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001055
OrthoInspector	1	1.000	-	-		otm45455
orthoMCL	1	0.900	-	-		OOG6_107717
Panther	1	1.100	-	-	LDO	PTHR23349
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1477
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	9.740