Protein Alignment twi and hand2

DIOPT Version :9

• Sequence 1: NP_001033967.1
• Gene: twi / 37655
• FlyBaseID: FBgn0003900
• Length: 490
• Species: Drosophila melanogaster
• Sequence 2: NP_571701.3
• Gene: hand2 / 58150
• ZFINID: ZDB-GENE-000511-1
• Length: 205
• Species: Danio rerio
• Alignment Length: 216
• Identity: 61/216 - (28%)
• Similarity: 95/216 - (43%)
• Gaps: 48/216 - (22%)

  Fly   256 PHQQSHAQMHFQNAYRQSFEGYEPANSLNGSAYSSSDRDDMEYARHNALSSVSDLN--GGVMSPA 318
            ||   |..||        .:||       ..|.:|...::..|. |..|.|..:::  ...|:|:
Zfish     8 PH---HPVMH--------HDGY-------SFAAASRCHEEPPYF-HGWLISHPEMSPPDYTMAPS 53

  Fly   319 CLADDGSAGSLLDGSDAGG----KAFRKPRRRLKRKPSKTEETDEFSNQRVMANVRERQRTQSLN 379
            ...:..:....||.|..||    .|.....|.:||:|:              ||.:||:||||:|
Zfish    54 YSPEYSTGAPGLDHSHYGGVPGAGAVGMGPRTVKRRPT--------------ANRKERRRTQSIN 104

  Fly   380 DAFKSLQQIIPTLPSD-KLSKIQTLKLATRYIDFLCRMLSSSDISLLKALEAQGSPSAYGSASSL 443
            .||..|::.||.:|:| |||||:||:|||.||.:|..:|...        |..|...|:.:....
Zfish   105 SAFAELRECIPNVPADTKLSKIKTLRLATSYIAYLMDILDKD--------EQNGETEAFKAEFKK 161

  Fly   444 LSAAANGAEADLKCLRKANGA 464
            ..|.....:.::..:.|::|:
Zfish   162 TDAKEERRKKEMNDVLKSSGS 182

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
twi	NP_001033967.1	HLH	363..413	CDD:278439	28/50 (56%)
hand2	NP_571701.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	76..103		12/40 (30%)
		HLH	88..139	CDD:278439	30/64 (47%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	158..194		3/25 (12%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170583735
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5507
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	4	3.830