Protein Alignment twi and ASCL3

DIOPT Version :10

• Sequence 1: NP_523816.2
• Gene: twi / 37655
• FlyBaseID: FBgn0003900
• Length: 490
• Species: Drosophila melanogaster
• Sequence 2: NP_065697.1
• Gene: ASCL3 / 56676
• HGNCID: 740
• Length: 181
• Species: Homo sapiens
• Alignment Length: 94
• Identity: 30/94 - (31%)
• Similarity: 54/94 - (57%)
• Gaps: 13/94 - (13%)

  Fly   360 FSNQRVMANVRERQRTQSLNDAFKSLQQIIPTLPSDK-LSKIQTLKLATRYIDFLCRMLSSSDIS 423
            |:.:|   |.|||||.:.:|:.:..|:..:|....:| |||::||:.|.:||::|..:|...
Human    94 FTRKR---NERERQRVKCVNEGYAQLRHHLPEEYLEKRLSKVETLRAAIKYINYLQSLLYPD--- 152

  Fly   424 LLKALEAQGSPSAYGSASSLLSAAANGAE 452
              || |.:.:|   |..||:::..::.|:
Human   153 --KA-ETKNNP---GKVSSMIATTSHHAD 175

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
twi	NP_523816.2	bHLH_TS_TWIST	363..421	CDD:381470	21/58 (36%)
ASCL3	NP_065697.1	bHLH_TS_ASCL3	91..149	CDD:381588	21/57 (37%)
		Basic motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU00981	93..106		7/14 (50%)
		Helix-loop-helix motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU00981	107..145		12/37 (32%)