Protein Alignment twi and olig3

DIOPT Version :10

• Sequence 1: NP_523816.2
• Gene: twi / 37655
• FlyBaseID: FBgn0003900
• Length: 490
• Species: Drosophila melanogaster
• Sequence 2: NP_001103863.1
• Gene: olig3 / 566728
• ZFINID: ZDB-GENE-080903-1
• Length: 255
• Species: Danio rerio
• Alignment Length: 240
• Identity: 68/240 - (28%)
• Similarity: 98/240 - (40%)
• Gaps: 64/240 - (26%)

  Fly   281 NSLNGSAYSSS-DRDDMEYARHN-------ALSSVSDLNGGVMSPACLADDGSAGSLLDGSDAGG 337
            ||.:.|:.||| |.|.|.:..|:       .|:|||.....::..       .|...|..:.:|.
Zfish     2 NSDSSSSRSSSPDMDGMYHHHHHHHHHQDGLLNSVSSTQNELLQK-------MASEHLSKTPSGS 59

  Fly   338 KAFRKPRRRLKRKPSKTEETDEFSNQRVMANVRERQRTQSLNDAFKSLQQIIPTL--PS-DKLSK 399
            |        .|.|...||:  |....|:..|.|||:|...||.|...|::::|..  || .||||
Zfish    60 K--------YKLKKQVTEQ--EIQQLRLKINGRERKRMHDLNLAMDGLREVMPYAHGPSVRKLSK 114

  Fly   400 IQTLKLATRYIDFLCRMLSSSDISLLKALEAQ---GSPSAY-------GSASS----------LL 444
            |.||.||..||     ::.:|.:..:|.|..:   |..||:       |.|.|          ||
Zfish   115 IATLLLARNYI-----LMLTSSLDEMKRLVGEIYGGHHSAFHCGTVSHGGAHSAGAAHQVHHPLL 174

  Fly   445 SAAANGAEAD------LKCLRKAN----GAPIIPPEKLSYLFGVW 479
            .:|.:|:.:.      |..:|..:    ..| .||.:|...|..|
Zfish   175 GSALSGSTSSTLSLPGLTSIRAPHTLMKSTP-TPPLQLGGSFQHW 218

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
twi	NP_523816.2	bHLH_TS_TWIST	363..421	CDD:381470	24/60 (40%)
olig3	NP_001103863.1	bHLH_TS_OLIG3	60..140	CDD:381511	33/94 (35%)