DRSC/TRiP Functional Genomics Resources

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Protein Alignment twi and twist1b

DIOPT Version :9

Sequence 1:NP_001033967.1 Gene:twi / 37655 FlyBaseID:FBgn0003900 Length:490 Species:Drosophila melanogaster
Sequence 2:NP_001017820.1 Gene:twist1b / 550518 ZFINID:ZDB-GENE-050417-357 Length:169 Species:Danio rerio


Alignment Length:214 Identity:78/214 - (36%)
Similarity:104/214 - (48%) Gaps:52/214 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly   278 EPANSLNGSAYSSSDRDDMEYARHNALSSVSDLNGGVMSPACLADDGSAGSLLDGSDAGGKAFRK 342
            |||...:.|..|.:|             |:|:.:|....|..........|..:|.|:......|
Zfish     4 EPARDSSSSPVSPAD-------------SLSNSDGEPDRPPKRCARKRRSSKKNGEDSDSSTLGK 55

  Fly   343 PRRRLKRKPSKTEETDEFSNQRVMANVRERQRTQSLNDAFKSLQQIIPTLPSDKLSKIQTLKLAT 407
            ..::.....:..:..:|...|||||||||||||||||:||.:|::|||||||||||||||||||.
Zfish    56 RGKKSSNSSNSPQSFEELQTQRVMANVRERQRTQSLNEAFAALRKIIPTLPSDKLSKIQTLKLAA 120

  Fly   408 RYIDFLCRMLSSSDISLLKALEAQGSPSAYGSASSLLSAAANGAEADLKCLRKANGAPIIPPEKL 472
            |||||||::|.|.:      |:::.:..:|                             :..|:|
Zfish   121 RYIDFLCQVLQSDE------LDSKMASCSY-----------------------------VAHERL 150

  Fly   473 SYLFGVWRMEG----DAQH 487
            ||.|.||||||    .|.|
Zfish   151 SYAFSVWRMEGAWSMSASH 169

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
twiNP_001033967.1 HLH 363..413 CDD:278439 43/49 (88%)
twist1bNP_001017820.1 HLH 76..126 CDD:278439 43/49 (88%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C170583774
Domainoid 1 1.000 91 1.000 Domainoid score I7661
eggNOG 1 0.900 - - E1_KOG4447
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0001055
OrthoInspector 1 1.000 - - otm25873
orthoMCL 1 0.900 - - OOG6_107717
Panther 1 1.100 - - LDO PTHR23349
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R5507
SonicParanoid 1 1.000 - - X1477
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
1110.770

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