Protein Alignment twi and Olig2

DIOPT Version :10

• Sequence 1: NP_523816.2
• Gene: twi / 37655
• FlyBaseID: FBgn0003900
• Length: 490
• Species: Drosophila melanogaster
• Sequence 2: NP_058663.2
• Gene: Olig2 / 50913
• MGIID: 1355331
• Length: 323
• Species: Mus musculus
• Alignment Length: 225
• Identity: 64/225 - (28%)
• Similarity: 92/225 - (40%)
• Gaps: 43/225 - (19%)

  Fly   282 SLNGSAYSSSDRDDMEYARHNALSSVSDLNGGVMSPACLAD------------DGSAGSLLDGSD 334
            ||..|..||.:.||:.....:...|.|...||.:|.:..:|            .|::|: ..|..
Mouse     6 SLVSSRPSSPEPDDLFLPARSKGGSSSGFTGGTVSSSTPSDCPPELSSELRGAMGASGA-HPGDK 69

  Fly   335 AGGKAFRKPRRRLK-----------RKPSKTEETDEFSNQRVMANVRERQRTQSLNDAFKSLQQI 388
            .||..|:.......           :|..|.....|....|:..|.|||:|...||.|...|:::
Mouse    70 LGGGGFKSSSSSTSSSTSSAATSSTKKDKKQMTEPELQQLRLKINSRERKRMHDLNIAMDGLREV 134

  Fly   389 IPTL--PS-DKLSKIQTLKLATRYIDFLCRMLSSSDISLLKAL--EAQGS------PSAYGS--- 439
            :|..  || .|||||.||.||..||     ::.::.:..:|.|  |..|.      |||.|.
Mouse   135 MPYAHGPSVRKLSKIATLLLARNYI-----LMLTNSLEEMKRLVSEIYGGHHAGFHPSACGGLAH 194

  Fly   440 ASSLLSAAANGAEADLKCLRKANGAPIIPP 469
            ::.|.:|.|:.|.|.......|...||:||
Mouse   195 SAPLPTATAHPAAAAHAAHHPAVHHPILPP 224

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
twi	NP_523816.2	bHLH_TS_TWIST	363..421	CDD:381470	24/60 (40%)
Olig2	NP_058663.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..107		22/101 (22%)
		bHLH_TS_OLIG2	95..179	CDD:381510	30/88 (34%)