Protein Alignment twi and NEUROG3

DIOPT Version :10

• Sequence 1: NP_523816.2
• Gene: twi / 37655
• FlyBaseID: FBgn0003900
• Length: 490
• Species: Drosophila melanogaster
• Sequence 2: NP_066279.2
• Gene: NEUROG3 / 50674
• HGNCID: 13806
• Length: 214
• Species: Homo sapiens
• Alignment Length: 141
• Identity: 46/141 - (32%)
• Similarity: 70/141 - (49%)
• Gaps: 21/141 - (14%)

  Fly   327 GSLLDGSDAGGKAFRKPRRRLKRKPSKTEETDEFS------NQRVMANVRERQRTQSLNDAFKSL 385
            |:..:..:.|.:.  .||:...|:..::....|.:      ::|..||.|||.|..:||.|..:|
Human    44 GNCAEAEEGGCRG--APRKLRARRGGRSRPKSELALSKQRRSRRKKANDRERNRMHNLNSALDAL 106

  Fly   386 QQIIPTLPSD-KLSKIQTLKLATRYIDFLCRMLSSSDISLLKALEAQ-----------GSPSAYG 438
            :.::||.|.| ||:||:||:.|..||..|.:.|..:|.||. |||..           |||..:|
Human   107 RGVLPTFPDDAKLTKIETLRFAHNYIWALTQTLRIADHSLY-ALEPPAPHCGELGSPGGSPGDWG 170

  Fly   439 SASSLLSAAAN 449
            |..|.:|.|.:
Human   171 SLYSPVSQAGS 181

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
twi	NP_523816.2	bHLH_TS_TWIST	363..421	CDD:381470	26/58 (45%)
NEUROG3	NP_066279.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..98		13/55 (24%)
		bHLH_TS_NGN3_ATOH5	77..144	CDD:381561	26/66 (39%)