DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment twi and Figla

DIOPT Version :9

Sequence 1:NP_001033967.1 Gene:twi / 37655 FlyBaseID:FBgn0003900 Length:490 Species:Drosophila melanogaster
Sequence 2:XP_575589.1 Gene:Figla / 500239 RGDID:1564754 Length:195 Species:Rattus norvegicus


Alignment Length:167 Identity:52/167 - (31%)
Similarity:69/167 - (41%) Gaps:43/167 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly   346 RLKRKP----SKTEETDEFSNQRVMANVRERQRTQSLNDAFKSLQQIIPTLP-SDKLSKIQTLKL 405
            ||||.|    |.|::......:|.:||.:||:|.::||..|..|:.::|.|| |.|.||:..||.
  Rat    40 RLKRLPSGGYSTTDDLHLVLERRRVANAKERERIKNLNRGFAKLKALVPFLPQSRKPSKVDILKG 104

  Fly   406 ATRYIDFLCRMLSSSDISLLKALEAQG-----------SPSAYGSASSLLSAAA--NGAEADLKC 457
            ||.||..|..:|..:     ||.|.||           |.....|...||..|.  .|..:.|| 
  Rat   105 ATEYIRILGCVLEGA-----KASEKQGPEEQQVHSSRPSDPHVSSTRELLGNATQPTGCASGLK- 163

  Fly   458 LRKANGAPIIPPEKLSYLFGVWRMEGDAQ----HQKA 490
              |....|             |...|.::    ||.|
  Rat   164 --KEEEGP-------------WAYGGHSELYSYHQSA 185

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
twiNP_001033967.1 HLH 363..413 CDD:278439 23/50 (46%)
FiglaXP_575589.1 bHLH_TS_FIGLA 62..117 CDD:381428 24/54 (44%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C166343509
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.840

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