Protein Alignment twi and Atoh1

DIOPT Version :10

• Sequence 1: NP_523816.2
• Gene: twi / 37655
• FlyBaseID: FBgn0003900
• Length: 490
• Species: Drosophila melanogaster
• Sequence 2: NP_001102708.1
• Gene: Atoh1 / 500156
• RGDID: 1565171
• Length: 351
• Species: Rattus norvegicus
• Alignment Length: 299
• Identity: 70/299 - (23%)
• Similarity: 109/299 - (36%)
• Gaps: 60/299 - (20%)

  Fly   227 EELPEHKAQVFLPLYNNQQQQSQQLQQQQPHQQSHAQMHFQNAYRQS---FEGYEPANSLNGSAY 288
            :||.:|          ::..|...:.|..|...:..|......|...   .:..:|...|..:..
  Rat    14 KELGDH----------HRHPQPHHIPQLTPQPPATLQARDHPVYPAELSLLDSTDPRAWLTPTLQ 68

  Fly   289 SSSDRDDMEYARHNALSSVSDLNGGVMSPACLADDGSAGSLLDGSDAGGKAFR----KPRRRL-- 347
            ........:|..|:.....|:    ..:|...||  ..|.|:..|..||.:..    |.|.:|
  Rat    69 GLCTARAAQYLLHSPELGASE----AAAPGDEAD--GQGELVRRSGCGGLSKSPGPVKVREQLCK 127

  Fly   348 --------------KRKPSKTEETDEFSNQRVMANVRERQRTQSLNDAFKSLQQIIPTLPSD-KL 397
                          :|.||..:.......:|:.||.|||:|...||.||..|:.:||:..:| ||
  Rat   128 LKGGVVVDELGCSRQRAPSSKQVNGVQKQRRLAANARERRRMHGLNHAFDQLRNVIPSFNNDKKL 192

  Fly   398 SKIQTLKLATRYIDFLCRMLSSSDISLLKALEAQGSPSAYGSASS---LLSAAANGAEADLKCLR 459
            ||.:||::|..||:.|..:|.:..:.      .|..|.|....:.   |.:||:....|....:.
  Rat   193 SKYETLQMAQIYINALSELLQTPSVG------EQPPPPAASCKNDHHHLRAAASYEGGAGASAVA 251

  Fly   460 KANGAP-----IIPPEKLSYLF------GVWRMEGDAQH 487
            .|..||     ..||......|      |.:.::.||.|
  Rat   252 GAQPAPGGGPRPTPPGACRTRFSTPASSGGYSVQLDALH 290

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
twi	NP_523816.2	bHLH_TS_TWIST	363..421	CDD:381470	26/58 (45%)
Atoh1	NP_001102708.1	bHLH_TS_ATOH1	152..215	CDD:381556	26/62 (42%)