Protein Alignment twi and NEUROD1

DIOPT Version :10

• Sequence 1: NP_523816.2
• Gene: twi / 37655
• FlyBaseID: FBgn0003900
• Length: 490
• Species: Drosophila melanogaster
• Sequence 2: NP_002491.3
• Gene: NEUROD1 / 4760
• HGNCID: 7762
• Length: 356
• Species: Homo sapiens
• Alignment Length: 94
• Identity: 35/94 - (37%)
• Similarity: 54/94 - (57%)
• Gaps: 6/94 - (6%)

  Fly   341 RKPRRRLKRKPSKTE-ETDEFSNQRVMANVRERQRTQSLNDAFKSLQQIIPTL-PSDKLSKIQTL 403
            :||:||..:|...|: ..:.|..:|:.||.|||.|...||.|..:|::::|.. .:.|||||:||
Human    79 QKPKRRGPKKKKMTKARLERFKLRRMKANARERNRMHGLNAALDNLRKVVPCYSKTQKLSKIETL 143

  Fly   404 KLATRYIDFLCRMLSSSD----ISLLKAL 428
            :||..||..|..:|.|..    :|.::.|
Human   144 RLAKNYIWALSEILRSGKSPDLVSFVQTL 172

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
twi	NP_523816.2	bHLH_TS_TWIST	363..421	CDD:381470	26/58 (45%)
NEUROD1	NP_002491.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..94		6/14 (43%)
		bHLH_TS_NeuroD1	75..160	CDD:381562	32/80 (40%)
		Nuclear localization signal. /evidence=ECO:0000255	87..93		1/5 (20%)
		Neuro_bHLH	160..284	CDD:463621	2/13 (15%)