Protein Alignment twi and twist2

DIOPT Version :10

• Sequence 1: NP_523816.2
• Gene: twi / 37655
• FlyBaseID: FBgn0003900
• Length: 490
• Species: Drosophila melanogaster
• Sequence 2: NP_001005956.1
• Gene: twist2 / 30395
• ZFINID: ZDB-GENE-980526-235
• Length: 163
• Species: Danio rerio
• Alignment Length: 213
• Identity: 80/213 - (37%)
• Similarity: 102/213 - (47%)
• Gaps: 64/213 - (30%)

  Fly   279 PANSLNGSAYSSSDRDDMEYARHNALSSVSDLNGGVMSPACLADDGSAGSLLDGSDAGGKAFRKP 343
            |.:||..|. ...||....:.|.......|            ::|.|:.|.::
Zfish    11 PVDSLVTSE-EELDRQQKRFGRKRRQGRKS------------SEDSSSPSSVN------------ 50

  Fly   344 RRRLKRKPSKTEETDEFSNQRVMANVRERQRTQSLNDAFKSLQQIIPTLPSDKLSKIQTLKLATR 408
            :|..|..||.|:..:|..||||:|||||||||||||:||.||::|||||||||||||||||||:|
Zfish    51 KRNKKPSPSSTQSFEELQNQRVLANVRERQRTQSLNEAFASLRKIIPTLPSDKLSKIQTLKLASR 115

  Fly   409 YIDFLCRMLSSSDISLLKALEAQGSPSAYGSASSLLSAAANGAEADLKCLRKANGAPIIPPEKLS 473
            ||||||::|.|.::.                                   .|.:....:..|:||
Zfish   116 YIDFLCQVLQSDEMD-----------------------------------NKMSSCSYVAHERLS 145

  Fly   474 YLFGVWRMEG----DAQH 487
            |.|.||||||    .|.|
Zfish   146 YAFSVWRMEGAWSMSASH 163

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
twi	NP_523816.2	bHLH_TS_TWIST	363..421	CDD:381470	48/57 (84%)
twist2	NP_001005956.1	bHLH_TS_TWIST1	59..135	CDD:381418	53/110 (48%)