Protein Alignment twi and twist1a

DIOPT Version :9

• Sequence 1: NP_001033967.1
• Gene: twi / 37655
• FlyBaseID: FBgn0003900
• Length: 490
• Species: Drosophila melanogaster
• Sequence 2: NP_571059.1
• Gene: twist1a / 30175
• ZFINID: ZDB-GENE-000210-6
• Length: 171
• Species: Danio rerio
• Alignment Length: 220
• Identity: 80/220 - (36%)
• Similarity: 103/220 - (46%)
• Gaps: 63/220 - (28%)

  Fly   264 MHFQNAYRQSFEGYEPANSLNGSAYSSSDRDDMEYARHNALSSVSDLNGGVMSPACLADDGSAGS 328
            ||..::..:|     |.:||..|......|.....:|....|..:            |:|..
Zfish     7 MHEDSSSPES-----PVDSLGNSEEELDRRQPKRVSRKKRASRKN------------AEDSD--- 51

  Fly   329 LLDGSDAGGKAFRKPRRRLKRKPSKTEETDEFSNQRVMANVRERQRTQSLNDAFKSLQQIIPTLP 393
                |...||..:|    .....|..:..::...|||||||||||||||||:||.||::||||||
Zfish    52 ----SPTPGKRSKK----CSNSSSSPQSLEDLQTQRVMANVRERQRTQSLNEAFASLRKIIPTLP 108

  Fly   394 SDKLSKIQTLKLATRYIDFLCRMLSSSDISLLKALEAQGSPSAYGSASSLLSAAANGAEADLKCL 458
            |||||||||||||.|||||||::|.|.:      |:::.|..:|
Zfish   109 SDKLSKIQTLKLAARYIDFLCQVLQSDE------LDSKMSSCSY--------------------- 146

  Fly   459 RKANGAPIIPPEKLSYLFGVWRMEG 483
                    :..|:|||.|.||||||
Zfish   147 --------VAHERLSYAFSVWRMEG 163

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
twi	NP_001033967.1	HLH	363..413	CDD:278439	44/49 (90%)
twist1a	NP_571059.1	HLH	78..128	CDD:278439	44/49 (90%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170583772
Domainoid	1	1.000	91	1.000	Domainoid score	I7661
eggNOG	1	0.900	-	-		E1_KOG4447
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001055
OrthoInspector	1	1.000	-	-		otm25873
orthoMCL	1	0.900	-	-		OOG6_107717
Panther	1	1.100	-	-	LDO	PTHR23349
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5507
SonicParanoid	1	1.000	-	-		X1477
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	10	9.770