Protein Alignment twi and twist1a

DIOPT Version :10

• Sequence 1: NP_523816.2
• Gene: twi / 37655
• FlyBaseID: FBgn0003900
• Length: 490
• Species: Drosophila melanogaster
• Sequence 2: NP_571059.1
• Gene: twist1a / 30175
• ZFINID: ZDB-GENE-000210-6
• Length: 171
• Species: Danio rerio
• Alignment Length: 220
• Identity: 80/220 - (36%)
• Similarity: 103/220 - (46%)
• Gaps: 63/220 - (28%)

  Fly   264 MHFQNAYRQSFEGYEPANSLNGSAYSSSDRDDMEYARHNALSSVSDLNGGVMSPACLADDGSAGS 328
            ||..::..:|     |.:||..|......|.....:|....|..:            |:|..
Zfish     7 MHEDSSSPES-----PVDSLGNSEEELDRRQPKRVSRKKRASRKN------------AEDSD--- 51

  Fly   329 LLDGSDAGGKAFRKPRRRLKRKPSKTEETDEFSNQRVMANVRERQRTQSLNDAFKSLQQIIPTLP 393
                |...||..:|    .....|..:..::...|||||||||||||||||:||.||::||||||
Zfish    52 ----SPTPGKRSKK----CSNSSSSPQSLEDLQTQRVMANVRERQRTQSLNEAFASLRKIIPTLP 108

  Fly   394 SDKLSKIQTLKLATRYIDFLCRMLSSSDISLLKALEAQGSPSAYGSASSLLSAAANGAEADLKCL 458
            |||||||||||||.|||||||::|.|.:      |:::.|..:|
Zfish   109 SDKLSKIQTLKLAARYIDFLCQVLQSDE------LDSKMSSCSY--------------------- 146

  Fly   459 RKANGAPIIPPEKLSYLFGVWRMEG 483
                    :..|:|||.|.||||||
Zfish   147 --------VAHERLSYAFSVWRMEG 163

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
twi	NP_523816.2	bHLH_TS_TWIST	363..421	CDD:381470	49/57 (86%)
twist1a	NP_571059.1	bHLH_SF	73..143	CDD:469605	50/75 (67%)