DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment twi and Tcf15

DIOPT Version :9

Sequence 1:	NP_001033967.1	Gene:	twi / 37655	FlyBaseID:	FBgn0003900	Length:	490	Species:	Drosophila melanogaster
Sequence 2:	NP_001162051.1	Gene:	Tcf15 / 296272	RGDID:	1308464	Length:	195	Species:	Rattus norvegicus

Alignment Length:	181	Identity:	62/181 - (34%)
Similarity:	80/181 - (44%)	Gaps:	35/181 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   320 LADDGSAGSLLDGSD------AGGKAFRK-PRRRLKRKPSKTEETDEFSNQRVMANVRERQRTQS 377
            |::|....|..|.||      .|.:|.|: |.....|:.|..........||..||.|||.||||
  Rat    21 LSEDEENRSESDASDQSFGCCEGLEAARRGPGPGSGRRASGGAGPVVVVRQRQAANARERDRTQS 85

  Fly   378 LNDAFKSLQQIIPTLPSD-KLSKIQTLKLATRYIDFLCRMLSSSDISLLKALEAQGSP--SAYGS 439
            :|.||.:|:.:|||.|.| |||||:||:||:.||..|..:|      ||......|.|  .|.|.
  Rat    86 VNTAFTALRTLIPTEPVDRKLSKIETLRLASSYIAHLANVL------LLGDAADDGQPCFRAAGG 144

  Fly   440 ASSLLSAA-----------------ANGAEADL--KCLRKANGAPIIPPEK 471
            ..|.:.||                 ..|:..||  .||:....||:..|.:
  Rat   145 GKSAVPAADGRQPRSICTFCLSNQRKGGSRRDLGGSCLKVRGVAPLRGPRR 195

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
twi	NP_001033967.1	HLH	363..413	CDD:278439	31/50 (62%)
Tcf15	NP_001162051.1	bHLH_TS_TCF15_paraxis	64..129	CDD:381476	34/70 (49%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166343511
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840