DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment twi and Neurog2

DIOPT Version :9

Sequence 1:	NP_001033967.1	Gene:	twi / 37655	FlyBaseID:	FBgn0003900	Length:	490	Species:	Drosophila melanogaster
Sequence 2:	XP_008759703.1	Gene:	Neurog2 / 295475	RGDID:	1309061	Length:	263	Species:	Rattus norvegicus

Alignment Length:	242	Identity:	70/242 - (28%)
Similarity:	102/242 - (42%)	Gaps:	60/242 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   279 PANSLNGSAYSSSDRDDMEYARHNALSSVSDLNGGVMSPACLADDGS-AGSLLDGSDAGGKAFRK 342
            ||::......||:|.::.|..|...              |.....|: ||..:.||.|.|....:
  Rat    25 PASATLTPMSSSADEEEDEELRRPG--------------AARGQRGAEAGQGVQGSSASGAGGCR 75

  Fly   343 PRRRL------KRKPS---------KTEETDE--FSNQRVMANVRERQRTQSLNDAFKSLQQIIP 390
            |.|.|      ||:||         ||.||.:  ...:|:.||.|||.|..:||.|..:|::::|
  Rat    76 PGRLLGLVHECKRRPSRARAVSRGAKTAETVQRIKKTRRLKANNRERNRMHNLNAALDALREVLP 140

  Fly   391 TLPSD-KLSKIQTLKLATRYIDFLCRMLSSSD------------------ISLLKALEAQG---S 433
            |.|.| ||:||:||:.|..||..|...|..:|                  :|...||.|.|   |
  Rat   141 TFPEDAKLTKIETLRFAHNYIWALTETLRLADHCAGGGSLQGALFSEAVLLSPGAALGASGDSPS 205

  Fly   434 PSAYGSASSLLSAAANGAEADLKCLRKANGAPII------PPEKLSY 474
            ||:..|.::..::::|........|..|:....:      ||||..|
  Rat   206 PSSSWSCTNSPASSSNSTSPYSCTLSPASPGSDVDYWQPPPPEKHRY 252

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
twi	NP_001033967.1	HLH	363..413	CDD:278439	24/50 (48%)
Neurog2	XP_008759703.1	HLH	110..169	CDD:238036	25/58 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910