DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment twi and Tcf15

DIOPT Version :9

Sequence 1:	NP_001033967.1	Gene:	twi / 37655	FlyBaseID:	FBgn0003900	Length:	490	Species:	Drosophila melanogaster
Sequence 2:	XP_006499163.1	Gene:	Tcf15 / 21407	MGIID:	104664	Length:	262	Species:	Mus musculus

Alignment Length:	236	Identity:	72/236 - (30%)
Similarity:	100/236 - (42%)	Gaps:	37/236 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   267 QNAYRQSFEGYEPANSLNGSAYSSSDRDDMEYARHNALSSVSDLNGGVMSP--ACLADDGSAGSL 329
            |:..|:....:|.|.:..|...|.:.|.:.......|.:.:..:...|:.|  ..|::|....|.
Mouse    33 QSVRRRPAGPWERAGAHGGGGGSGTRRVEARGRAPMAFALLRPVGAHVLYPDVRLLSEDEENRSE 97

  Fly   330 LDGSD------AGGKAFRK-PRRRLKRKPSKTEETDEFSNQRVMANVRERQRTQSLNDAFKSLQQ 387
            .|.||      .|.:|.|: |.....|:.|..........||..||.|||.||||:|.||.:|:.
Mouse    98 SDASDQSFGCCEGLEAARRGPGPGSGRRASNGAGPVVVVRQRQAANARERDRTQSVNTAFTALRT 162

  Fly   388 IIPTLPSD-KLSKIQTLKLATRYIDFLCRMLSSSDISLLKALEAQGSP--SAYGSASSLLSAA-- 447
            :|||.|.| |||||:||:||:.||..|..:|      ||......|.|  .|.|...|.:.||
Mouse   163 LIPTEPVDRKLSKIETLRLASSYIAHLANVL------LLGDAADDGQPCFRAAGGGKSAVPAADG 221

  Fly   448 ---------------ANGAEADL--KCLRKANGAPIIPPEK 471
                           ..|:..||  .||:....||:..|.:
Mouse   222 RQPRSICTFCLSNQRKGGSRRDLGGSCLKVRGVAPLRGPRR 262

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
twi	NP_001033967.1	HLH	363..413	CDD:278439	31/50 (62%)
Tcf15	XP_006499163.1	bHLH_TS_TCF15_paraxis	131..196	CDD:381476	34/70 (49%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167839689
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840