DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment twi and Neurog1

DIOPT Version :9

Sequence 1:	NP_001033967.1	Gene:	twi / 37655	FlyBaseID:	FBgn0003900	Length:	490	Species:	Drosophila melanogaster
Sequence 2:	NP_035026.1	Gene:	Neurog1 / 18014	MGIID:	107754	Length:	244	Species:	Mus musculus

Alignment Length:	169	Identity:	56/169 - (33%)
Similarity:	79/169 - (46%)	Gaps:	29/169 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   286 SAYSSSD-----RDDMEYARHNALSSVSDLNGGVMSPACLADDGSAGSLLDGSDAGGKAFRKPRR 345
            |:.||||     .|:.:.||...|:|.|    |:..||    ..||.:|...|:..|....:..|
Mouse    16 SSNSSSDLSSFLTDEEDCARLQPLASTS----GLSVPA----RRSAPALSGASNVPGAQDEEQER 72

  Fly   346 RLKRKPSKTEETDEF----SNQRVMANVRERQRTQSLNDAFKSLQQIIPTLPSD-KLSKIQTLKL 405
            |.:|..::.......    .::||.||.|||.|..:||.|..:|:.::|:.|.| ||:||:||:.
Mouse    73 RRRRGRARVRSEALLHSLRRSRRVKANDRERNRMHNLNAALDALRSVLPSFPDDTKLTKIETLRF 137

  Fly   406 ATRYIDFLCRMLSSSDISLLKALEAQGSPSAYGSASSLL 444
            |..||..|...|..:|         ||.|.  |||...|
Mouse   138 AYNYIWALAETLRLAD---------QGLPG--GSARERL 165

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
twi	NP_001033967.1	HLH	363..413	CDD:278439	24/50 (48%)
Neurog1	NP_035026.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..27		5/10 (50%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	39..82		14/50 (28%)
		HLH	91..150	CDD:238036	25/58 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910