Protein Alignment twi and Msc

DIOPT Version :10

• Sequence 1: NP_523816.2
• Gene: twi / 37655
• FlyBaseID: FBgn0003900
• Length: 490
• Species: Drosophila melanogaster
• Sequence 2: NP_001398640.1
• Gene: Msc / 17681
• MGIID: 1333884
• Length: 238
• Species: Mus musculus
• Alignment Length: 193
• Identity: 58/193 - (30%)
• Similarity: 78/193 - (40%)
• Gaps: 46/193 - (23%)

  Fly   286 SAYSSSDRDDME------------------------YARHNALSSVSDLNGGVMSPACLADDGSA 326
            |..|.||.:|.|                        |...:.:||..: ..|...|..|   |:|
Mouse     2 STGSVSDPEDSEMRGLQRVYPAPASKRPPLLRMERGYGSPSDISSAEE-EDGEEEPGSL---GAA 62

  Fly   327 GSL----LDGSDAGGKAFRKPRRRLKRKPSKTEETDEFSNQRVMANVRERQRTQSLNDAFKSLQQ 387
            |..    |.|:||||...|......|..|.|....:...:||..||.|||.|.:.|:.||..|:.
Mouse    63 GGCKRKRLRGADAGGAGGRAGGAGKKPLPPKGSAAECKQSQRNAANARERARMRVLSKAFSRLKT 127

  Fly   388 IIPTLPSD-KLSKIQTLKLATRYIDFLCRMLSSSD------------ISLLKALEAQGSPSAY 437
            .:|.:|.| ||||:.||:||:.||..| |.|...|            :.:|::.....||..|
Mouse   128 SLPWVPPDTKLSKLDTLRLASSYIAHL-RQLLQEDRYEDSYVHPVNLVGMLRSRPGDSSPERY 189

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
twi	NP_523816.2	bHLH_TS_TWIST	363..421	CDD:381470	28/58 (48%)
Msc	NP_001398640.1	bHLH_TS_musculin	100..165	CDD:381546	29/65 (45%)