Protein Alignment twi and Twist2

DIOPT Version :10

• Sequence 1: NP_523816.2
• Gene: twi / 37655
• FlyBaseID: FBgn0003900
• Length: 490
• Species: Drosophila melanogaster
• Sequence 2: NP_031881.1
• Gene: Twist2 / 13345
• MGIID: 104685
• Length: 160
• Species: Mus musculus
• Alignment Length: 213
• Identity: 74/213 - (34%)
• Similarity: 98/213 - (46%)
• Gaps: 67/213 - (31%)

  Fly   279 PANSLNGSAYSSSDRDDMEYARHNALSSVSDLNGGVMSPACLADDGSAGSLLDGSDAGGKAFRKP 343
            |.:|| |::....:|....:.|....|..|            ::|||.               .|
Mouse    11 PVDSL-GTSEEELERQPKRFGRKRRYSKKS------------SEDGSP---------------TP 47

  Fly   344 RRRLKRKPSKTEETDEFSNQRVMANVRERQRTQSLNDAFKSLQQIIPTLPSDKLSKIQTLKLATR 408
            .:|.|:.....:..:|..:||::|||||||||||||:||.:|::|||||||||||||||||||.|
Mouse    48 GKRGKKGSPSAQSFEELQSQRILANVRERQRTQSLNEAFAALRKIIPTLPSDKLSKIQTLKLAAR 112

  Fly   409 YIDFLCRMLSSSDISLLKALEAQGSPSAYGSASSLLSAAANGAEADLKCLRKANGAPIIPPEKLS 473
            |||||.::|.|.::.                                   .|......:..|:||
Mouse   113 YIDFLYQVLQSDEMD-----------------------------------NKMTSCSYVAHERLS 142

  Fly   474 YLFGVWRMEG----DAQH 487
            |.|.||||||    .|.|
Mouse   143 YAFSVWRMEGAWSMSASH 160

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
twi	NP_523816.2	bHLH_TS_TWIST	363..421	CDD:381470	45/57 (79%)
Twist2	NP_031881.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..63		14/79 (18%)
		bHLH_TS_TWIST2	51..132	CDD:381543	48/115 (42%)