Protein Alignment twi and BHLHE23

DIOPT Version :10

• Sequence 1: NP_523816.2
• Gene: twi / 37655
• FlyBaseID: FBgn0003900
• Length: 490
• Species: Drosophila melanogaster
• Sequence 2: NP_542173.2
• Gene: BHLHE23 / 128408
• HGNCID: 16093
• Length: 241
• Species: Homo sapiens
• Alignment Length: 215
• Identity: 64/215 - (29%)
• Similarity: 89/215 - (41%)
• Gaps: 53/215 - (24%)

  Fly   268 NAYRQSFEGYEPANSLNGSAYSSSDRDDMEYAR-HNALSSVSDLNGGVMSPACLADDGSAGSLLD 331
            :||.....||..|.:  |.||.::  .:.|.|| :.......||..   :||..|...:|.|  .
Human    26 DAYLALSHGYAAAAA--GLAYGAA--REPEAARGYGTPGPGGDLPA---APAPRAPAQAAES--S 81

  Fly   332 GSDAGGK--AFRKPRRRL--------KRKPSKTEETDEFSNQRVMANVRERQRTQSLNDAFKSLQ 386
            |..:|.:  ||.:.|||.        :|:|.      |..:.|:..|.|||:|...||||...|:
Human    82 GEQSGDEDDAFEQRRRRRGPGSAADGRRRPR------EQRSLRLSINARERRRMHDLNDALDGLR 140

  Fly   387 QIIPTLPSD---KLSKIQTLKLATRYIDFLCRMLSSSDISLLKALEAQGSPSAYGSASSLLSAAA 448
            .:||...|.   |||||.||.||..||  |.:..:..::..|.|...||.    |.|:.:
Human   141 AVIPYAHSPSVRKLSKIATLLLAKNYI--LMQAQALDEMRRLVAFLNQGQ----GLAAPV----- 194

  Fly   449 NGAEADLKCLRKANGAPIIP 468
                         |.||:.|
Human   195 -------------NAAPLTP 201

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
twi	NP_523816.2	bHLH_TS_TWIST	363..421	CDD:381470	26/60 (43%)
BHLHE23	NP_542173.2	bHLH_SF	111..191	CDD:469605	33/91 (36%)