Protein Alignment twi and Neurog3

DIOPT Version :10

• Sequence 1: NP_523816.2
• Gene: twi / 37655
• FlyBaseID: FBgn0003900
• Length: 490
• Species: Drosophila melanogaster
• Sequence 2: NP_033849.3
• Gene: Neurog3 / 11925
• MGIID: 893591
• Length: 214
• Species: Mus musculus
• Alignment Length: 207
• Identity: 60/207 - (28%)
• Similarity: 84/207 - (40%)
• Gaps: 41/207 - (19%)

  Fly   256 PHQQSHAQMHFQNAYRQSFEGYEPANSLNGSAYSSSDRDDMEYARHNALSSVSDLNGGVMSPACL 320
            ||......:......:|.|.|             :||        |..|||    |....||..:
Mouse     3 PHPLDALTIQVSPETQQPFPG-------------ASD--------HEVLSS----NSTPPSPTLI 42

  Fly   321 ADDGSAGSLLD--GSDAGGKAFRKPRRRLKRKPSKTEETDEFSNQRVMANVRERQRTQSLNDAFK 383
            ..|.|...:.|  |:....:|.|..|.|.|   |:...:.:..::|..||.|||.|..:||.|..
Mouse    43 PRDCSEAEVGDCRGTSRKLRARRGGRNRPK---SELALSKQRRSRRKKANDRERNRMHNLNSALD 104

  Fly   384 SLQQIIPTLPSD-KLSKIQTLKLATRYIDFLCRMLSSSDISLL----------KALEAQGSPSAY 437
            :|:.::||.|.| ||:||:||:.|..||..|.:.|..:|.|..          ......||...:
Mouse   105 ALRGVLPTFPDDAKLTKIETLRFAHNYIWALTQTLRIADHSFYGPEPPVPCGELGSPGGGSNGDW 169

  Fly   438 GSASSLLSAAAN 449
            ||..|.:|.|.|
Mouse   170 GSIYSPVSQAGN 181

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
twi	NP_523816.2	bHLH_TS_TWIST	363..421	CDD:381470	26/58 (45%)
Neurog3	NP_033849.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..98		31/122 (25%)
		bHLH_TS_NGN3_ATOH5	77..144	CDD:381561	26/66 (39%)