DRSC/TRiP Functional Genomics Resources

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Protein Alignment twi and Neurod6

DIOPT Version :10

Sequence 1:NP_523816.2 Gene:twi / 37655 FlyBaseID:FBgn0003900 Length:490 Species:Drosophila melanogaster
Sequence 2:NP_033847.1 Gene:Neurod6 / 11922 MGIID:106593 Length:337 Species:Mus musculus


Alignment Length:127 Identity:38/127 - (29%)
Similarity:57/127 - (44%) Gaps:29/127 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly   344 RRRLKRKPSKTEETDEFSNQRVMANVRERQRTQSLNDAFKSLQQIIPTL-PSDKLSKIQTLKLAT 407
            ||.|::|.:.....:....:|..||.|||.|...||||..:|::::|.. .:.|||||:||:||.
Mouse    76 RRGLRKKKTTKLRLERVKFRRQEANARERNRMHGLNDALDNLRKVVPCYSKTQKLSKIETLRLAK 140

  Fly   408 RYI-------------------DFLCRMLSSSDISLLKA---------LEAQGSPSAYGSAS 441
            .||                   ..||:.||....:|:..         |..||..:|:.:.|
Mouse   141 NYIWALSEILRIGKRPDLLTFVQNLCKGLSQPTTNLVAGCLQLNARSFLMGQGGEAAHHTRS 202

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
twiNP_523816.2 bHLH_TS_TWIST 363..421 CDD:381470 28/77 (36%)
Neurod6NP_033847.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 28..80 2/3 (67%)
Nuclear localization signal. /evidence=ECO:0000255 80..86 1/5 (20%)
bHLH_TS_NeuroD6_ATOH2 82..151 CDD:381565 25/68 (37%)
Neuro_bHLH 153..272 CDD:463621 10/50 (20%)

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