Protein Alignment twi and Ptf1a

DIOPT Version :10

• Sequence 1: NP_523816.2
• Gene: twi / 37655
• FlyBaseID: FBgn0003900
• Length: 490
• Species: Drosophila melanogaster
• Sequence 2: NP_446416.1
• Gene: Ptf1a / 117034
• RGDID: 621709
• Length: 326
• Species: Rattus norvegicus
• Alignment Length: 329
• Identity: 89/329 - (27%)
• Similarity: 136/329 - (41%)
• Gaps: 71/329 - (21%)

  Fly   190 IYVDYLPTTVDEVASAQSCPGVQSTCTSPQSHFD----FPDEELPEHKAQVFLPLYNNQQQQSQQ 250
            :.:::.|..:|               |.|.|:||    |.|:...:       ||.:..:....
  Rat     4 VLLEHFPGALD---------------TFPSSYFDEEDFFTDQSSRD-------PLEDGDELLGD- 45

  Fly   251 LQQQQPHQQSHAQMHFQNAYRQSFEG----YEPANSLNGSAYSS---SDRDDMEYARHNALSSVS 308
             :|.:....|| |:| :..||   :|    .:||.|....|.:.   .|..:.|.:......:.:
  Rat    46 -EQAEVEFLSH-QLH-EYCYR---DGACLLLQPAPSAAPHALAPPPLGDPGEPEDSGSYCCDAGA 104

  Fly   309 DLNGGVMS----PACLA-------DDGSAGSLLDGSDAGGKAFRKPRRRLKRKPSKTEETDEFSN 362
            .|.....|    |:|||       ..|:....|:|:.|...|..:.|||::.:.       |...
  Rat   105 PLGAFPYSPGSPPSCLAYPCTAVLSPGTRLRGLNGAAAAAAAAARRRRRVRSEA-------ELQQ 162

  Fly   363 QRVMANVRERQRTQSLNDAFKSLQQIIPTLPSDK-LSKIQTLKLATRYIDFLCRMLSSSDISLLK 426
            .|..||||||:|.||:||||:.|:..|||||.:| |||:.||:||..||:||..:: .:|:
  Rat   163 LRQAANVRERRRMQSINDAFEGLRSHIPTLPYEKRLSKVDTLRLAIGYINFLSELV-QADL---- 222

  Fly   427 ALEAQGSPSAYGSASSLL---SAAANGAEADLKCLRKANG-APIIPPEKLSYLFG---VWRMEGD 484
            .|...|:....|...|..   .:..|.|:..:.|.|.... :|..|...|..|.|   .|..|..
  Rat   223 PLRGSGTGGCGGPGGSRHLGGDSPGNQAQKVIICHRGTRSPSPSDPDYGLPPLAGHSLSWADEKQ 287

  Fly   485 AQHQ 488
            .:.|
  Rat   288 LKEQ 291

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
twi	NP_523816.2	bHLH_TS_TWIST	363..421	CDD:381470	32/58 (55%)
Ptf1a	NP_446416.1	bHLH_TS_PTF1A	164..218	CDD:381423	32/53 (60%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	229..249		2/19 (11%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	304..326