Protein Alignment twi and neurog2

DIOPT Version :10

• Sequence 1: NP_523816.2
• Gene: twi / 37655
• FlyBaseID: FBgn0003900
• Length: 490
• Species: Drosophila melanogaster
• Sequence 2: XP_002934289.2
• Gene: neurog2 / 100493110
• XenbaseID: XB-GENE-491040
• Length: 213
• Species: Xenopus tropicalis
• Alignment Length: 212
• Identity: 64/212 - (30%)
• Similarity: 93/212 - (43%)
• Gaps: 35/212 - (16%)

  Fly   293 RDDMEYARHNALSSVSDLNGGVMSPA--CLADD----GSAGSLLDGSDAGGKAFRKPRRRLKRKP 351
            ||:.|.....:..|||..:   ||||  |.:||    ......|....|..:....|.|| .|..
 Frog     9 RDEEEELTSASPCSVSSSH---MSPAQTCSSDDEQLLSPTSPALMHLQAQEQENSPPSRR-SRPR 69

  Fly   352 SKTEET--DEFSNQRVMANVRERQRTQSLNDAFKSLQQIIPTLPSD-KLSKIQTLKLATRYIDFL 413
            :|..||  .....:|:.||.|||.|...||.|..||::::|:||.| ||:||:||:.|..||..|
 Frog    70 TKNGETVLKVKKTRRIKANNRERNRMHHLNSALDSLREVLPSLPEDAKLTKIETLRFAYNYIWAL 134

  Fly   414 CRML-------SSSDISLLKALEAQGSPSAYGSASSLLSAAANGAEADLKCLRKANGAPIIPPEK 471
            ...|       |:|.:|.:...::..|.|...|.||..|::.            .:.:|..|...
 Frog   135 SETLRLAEHGSSASTLSPMSVQDSSPSQSPSWSCSSSPSSSC------------GSFSPASPASS 187

  Fly   472 LSYLFGVWRMEGDAQHQ 488
            .|.:...|:   .|:|:
 Frog   188 TSDMLEYWQ---PAEHR 201

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
twi	NP_523816.2	bHLH_TS_TWIST	363..421	CDD:381470	28/65 (43%)
neurog2	XP_002934289.2	bHLH_TS_NGN2_ATOH4	74..142	CDD:381560	29/67 (43%)