Protein Alignment twi and atoh1

DIOPT Version :10

• Sequence 1: NP_523816.2
• Gene: twi / 37655
• FlyBaseID: FBgn0003900
• Length: 490
• Species: Drosophila melanogaster
• Sequence 2: XP_004911142.1
• Gene: atoh1 / 100488309
• XenbaseID: XB-GENE-6452084
• Length: 260
• Species: Xenopus tropicalis
• Alignment Length: 249
• Identity: 68/249 - (27%)
• Similarity: 89/249 - (35%)
• Gaps: 94/249 - (37%)

  Fly   301 HNALSSVSDLNGGVMSPACLADDGSAGSLLDGSD-------------------AGGKAFRKPRRR 346
            |.|.:...:|......|..|..|    .|||.||                   ..|:| .|.|..
 Frog     6 HGAAADWCELKELPSEPGLLGRD----YLLDSSDPRSWLSAASLQSRPEYVLHPQGRA-HKVREL 65

  Fly   347 LKRK------PSKTEETDEFSNQ--------------------RVMANVRERQRTQSLNDAFKSL 385
            .|.|      ..:.||.||.:::                    |:.||.|||:|...||.||..|
 Frog    66 CKLKGLQDEEDEEEEEDDEETSEGLCRHRGGPGKGPGGVQKQRRLAANARERRRMHGLNHAFDQL 130

  Fly   386 QQIIPTLPSD-KLSKIQTLKLATRYIDFLCRMLSSSDISLLKA--------------LEAQGSPS 435
            :.:||:..:| ||||.:||::|..||:.|      ||  ||:|              |.:.|.|.
 Frog   131 RNVIPSFNNDKKLSKYETLQMAQIYINAL------SD--LLQAPPDTRDPPCPPTYQLHSGGEPR 187

  Fly   436 AYGSASSLLSAAANGAEADLKCLRKANGAPIIPPEKLSYLFGVWRMEGDAQHQK 489
            ...|||               |.|.:...|...|  ||:.|    .||....||
 Frog   188 LAQSAS---------------CRRFSGDFPGQSP--LSFQF----QEGAGLSQK 220

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
twi	NP_523816.2	bHLH_TS_TWIST	363..421	CDD:381470	25/78 (32%)
atoh1	XP_004911142.1	bHLH_TS_ATOH1	103..166	CDD:381556	29/70 (41%)