DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment twi and neurod4

DIOPT Version :9

Sequence 1:	NP_001033967.1	Gene:	twi / 37655	FlyBaseID:	FBgn0003900	Length:	490	Species:	Drosophila melanogaster
Sequence 2:	NP_001124513.1	Gene:	neurod4 / 100124310	XenbaseID:	XB-GENE-972704	Length:	316	Species:	Xenopus tropicalis

Alignment Length:	156	Identity:	48/156 - (30%)
Similarity:	74/156 - (47%)	Gaps:	30/156 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   291 SDRDDMEYARHNALSSVSDLNGGVMSPACLADDGSAGSLLDGSDAGGKAFRKPRRRLKRKPSKTE 355
            |.:|:||   .|...|..|:..|:......:.||...   |..:..|:   ||::|..:|...|:
Frog    16 SSQDEME---RNQRQSAYDIISGLSHEERCSIDGEDD---DEEEEDGE---KPKKRGPKKKKMTK 71

  Fly   356 -ETDEFSNQRVMANVRERQRTQSLNDAFKSLQQIIPTL-PSDKLSKIQTLKLATRYI-------- 410
             ..:.|..:||.||.|||.|...||||.::|::::|.. .:.|||||:||:||..||
Frog    72 ARLERFRVRRVKANARERTRMHGLNDALENLRRVMPCYSKTQKLSKIETLRLARNYIWALSDILE 136

  Fly   411 -----------DFLCRMLSSSDISLL 425
                       :.||:.||....:|:
Frog   137 QGQSTEGKGFLEMLCKGLSQPTSNLV 162

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
twi	NP_001033967.1	HLH	363..413	CDD:278439	25/69 (36%)
neurod4	NP_001124513.1	bHLH_TS_NeuroD4_ATOH3	<69..137	CDD:381564	27/67 (40%)
neurod4	NP_001124513.1	Neuro_bHLH	138..256	CDD:372170	5/25 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910