Protein Alignment twi and hand2

DIOPT Version :10

• Sequence 1: NP_523816.2
• Gene: twi / 37655
• FlyBaseID: FBgn0003900
• Length: 490
• Species: Drosophila melanogaster
• Sequence 2: NP_001093695.1
• Gene: hand2 / 100101704
• XenbaseID: XB-GENE-481426
• Length: 210
• Species: Xenopus tropicalis
• Alignment Length: 170
• Identity: 55/170 - (32%)
• Similarity: 81/170 - (47%)
• Gaps: 56/170 - (32%)

  Fly   262 AQMHFQNAYRQSFEGYEPAN-SLNGSAYSSSDRDDMEYARHNALSSVSDLNGGVMSPACLADDGS 325
            ::.|.:|.|   |.|:..:: .::...||.:.....|||                       :|:
 Frog    29 SRCHEENPY---FHGWLISHPEMSPPDYSMAPSYSPEYA-----------------------NGA 67

  Fly   326 AGSLLD--------GSDAGGKAFRKPRRRLKRKPSKTEETDEFSNQRVMANVRERQRTQSLNDAF 382
            ||  ||        ||.|||         |.::|.|         :|..||.:||:||||:|.||
 Frog    68 AG--LDHSHYGGVPGSGAGG---------LMQRPVK---------RRGTANRKERRRTQSINSAF 112

  Fly   383 KSLQQIIPTLPSD-KLSKIQTLKLATRYIDFLCRMLSSSD 421
            ..|::.||.:|:| |||||:||:|||.||.:|..:|:..|
 Frog   113 AELRECIPNVPADTKLSKIKTLRLATSYIAYLMDLLAKDD 152

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
twi	NP_523816.2	bHLH_TS_TWIST	363..421	CDD:381470	31/58 (53%)
hand2	NP_001093695.1	bHLH_TS_HAND2	93..154	CDD:381477	32/60 (53%)