DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG42741 and zgc:153115

DIOPT Version :9

Sequence 1:	NP_611747.2	Gene:	CG42741 / 37654	FlyBaseID:	FBgn0261705	Length:	362	Species:	Drosophila melanogaster
Sequence 2:	NP_001070797.2	Gene:	zgc:153115 / 768186	ZFINID:	ZDB-GENE-061013-418	Length:	250	Species:	Danio rerio

Alignment Length:	272	Identity:	83/272 - (30%)
Similarity:	108/272 - (39%)	Gaps:	71/272 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   107 FSPFFAA--------SPFFFTYRRISGSGSGNGTGSVSVKQEDNNNSCSYNNGSSSGGAG--SAA 161
            :|.:.||        .|.......:||:......|..:.:.:.::............||.  :.|
Zfish     5 YSDYLAAECLVSISSGPVLHRPTPVSGAAQAPPQGLPAGEPDGSSEDREVRETLRLDGANMMTVA 69

  Fly   162 NSMQDYESKFSLLSLFKNPYKFAGGDG---QASRKTSPT---GGSSKPLASNSSPSWKSYAGSGS 220
            ..:.|...||..:|.:......:.|:.   ..|..|:||   ..|:.|:...|...|
Zfish    70 EILTDLHGKFRPMSAYSESSNSSCGESGYTTLSDSTTPTPTMTPSATPVPGQSQQIW-------- 126

  Fly   221 PHAALNPAFGGMGRGATRKDNSSFSGINFGGGGSAFGFTTSSDSMANGGYNDLSKNRKVHKCDTE 285
                                         ||||:....|                  |.|.|..:
Zfish   127 -----------------------------GGGGAPRSPT------------------KRHPCTFD 144

  Fly   286 GCDKVYTKSSHLKAHKRTHTGEKPYVCTWEGCIWRFARSDELTRHYRKHTGVKPFRCQLCTRSFS 350
            |||:||.||||||||.||||||:|:.|||..|..:|||||||.||.|.|||.|.|.|.||.:.|.
Zfish   145 GCDRVYGKSSHLKAHIRTHTGERPFPCTWPECEKKFARSDELARHLRTHTGEKRFLCPLCDKRFM 209

  Fly   351 RSDHLSLHMRRH 362
            |||||..|.|||
Zfish   210 RSDHLIKHARRH 221

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42741	NP_611747.2	COG5048	<273..>352	CDD:227381	46/78 (59%)
		zf-C2H2	280..304	CDD:278523	16/23 (70%)
		C2H2 Zn finger	282..304	CDD:275368	15/21 (71%)
		zf-H2C2_2	296..>313	CDD:290200	12/16 (75%)
		C2H2 Zn finger	312..334	CDD:275368	14/21 (67%)
		zf-H2C2_2	326..351	CDD:290200	14/24 (58%)
		C2H2 Zn finger	342..362	CDD:275368	11/19 (58%)
zgc:153115	NP_001070797.2	C2H2 Zn finger	144..163	CDD:275368	14/18 (78%)
		COG5048	153..>201	CDD:227381	33/47 (70%)
		zf-H2C2_2	155..182	CDD:290200	17/26 (65%)
		C2H2 Zn finger	171..193	CDD:275368	14/21 (67%)
		zf-H2C2_2	185..208	CDD:290200	13/22 (59%)
		zf-C2H2	199..221	CDD:278523	12/21 (57%)
		C2H2 Zn finger	201..221	CDD:275368	11/19 (58%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910