DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42741 and Klf17

DIOPT Version :9

Sequence 1:	NP_611747.2	Gene:	CG42741 / 37654	FlyBaseID:	FBgn0261705	Length:	362	Species:	Drosophila melanogaster
Sequence 2:	NP_083692.2	Gene:	Klf17 / 75753	MGIID:	2181068	Length:	341	Species:	Mus musculus

Alignment Length:	347	Identity:	92/347 - (26%)
Similarity:	131/347 - (37%)	Gaps:	98/347 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 RASTSHG----SSSSSYKFSS-ANKAVGY-SNGKPGGSSGSSSSSGFGAGSAGSSSLGAFAAQQQ 93
            |:...||    |..:...|.: ..:::|. |:..|.||||:     .|...:.|.:|     ..|
Mouse    71 RSLPEHGVRCPSQLAPIPFQNYCQRSIGRGSHVMPVGSSGT-----LGVTISFSENL-----MPQ 125

  Fly    94 QQLYASSGVSKL----------PFSPFFAASPFFFTYRRISGSGSGNGTGSVSVKQEDNNNSCSY 148
            ..|.:|.|||.:          |..|...|:                 |||:       .:....
Mouse   126 GGLPSSRGVSVMAHSSAPAMPYPMPPTVPAT-----------------TGSL-------KHGILL 166

  Fly   149 NNGSSSGGAGSAANSMQDYESKFSLLSLFKNPYKFAGGDGQASRKTSPTGGSSKPLASNSSPSWK 213
            ..|.:|.|..:.|..|.......:..:....|.:|        ::..|. .|...|.:.|:...:
Mouse   167 VPGMASAGTHAVAPFMDQMLHSINPCNPEMLPARF--------QQLLPL-DSQDSLVTESNTQEE 222

  Fly   214 SYA---GSGSPHAALNPAFGGMGRGATRKDNSSFSGINFGGGGSAFGFTTSSDSMANGGYNDLSK 275
            .:.   .:.:|..|.:|:   ..|||||:.                                 |.
Mouse   223 PFVREPPTPAPEGAESPS---TSRGATRRQ---------------------------------SP 251

  Fly   276 NRKVHKCDTEGCDKVYTKSSHLKAHKRTHTGEKPYVCTWEGCIWRFARSDELTRHYRKHTGVKPF 340
            ..:.:.|....|.|.|||.|||.:|:|.|||.||:.|.|.||.|:|.|||||.||.|.||..:|.
Mouse   252 VSRPYVCTYNSCGKSYTKRSHLVSHQRKHTGVKPFACDWNGCTWKFFRSDELGRHKRIHTRYRPH 316

  Fly   341 RCQLCTRSFSRSDHLSLHMRRH 362
            :|..|.|.|.|||||..|.|.|
Mouse   317 KCDECDREFMRSDHLRQHKRTH 338

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42741	NP_611747.2	COG5048	<273..>352	CDD:227381	38/78 (49%)
		zf-C2H2	280..304	CDD:278523	11/23 (48%)
		C2H2 Zn finger	282..304	CDD:275368	11/21 (52%)
		zf-H2C2_2	296..>313	CDD:290200	9/16 (56%)
		C2H2 Zn finger	312..334	CDD:275368	14/21 (67%)
		zf-H2C2_2	326..351	CDD:290200	12/24 (50%)
		C2H2 Zn finger	342..362	CDD:275368	11/19 (58%)
Klf17	NP_083692.2	COG5048	<22..317	CDD:227381	80/324 (25%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	214..252		10/73 (14%)
		zf-C2H2	256..280	CDD:278523	11/23 (48%)
		C2H2 Zn finger	261..280	CDD:275368	10/18 (56%)
		C2H2 Zn finger	288..310	CDD:275368	14/21 (67%)
		zf-H2C2_2	302..325	CDD:290200	11/22 (50%)
		zf-C2H2	316..338	CDD:278523	11/21 (52%)
		C2H2 Zn finger	318..338	CDD:275368	11/19 (58%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167841541
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23235
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	4	3.900