DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42741 and sr

DIOPT Version :9

Sequence 1:	NP_611747.2	Gene:	CG42741 / 37654	FlyBaseID:	FBgn0261705	Length:	362	Species:	Drosophila melanogaster
Sequence 2:	NP_001262693.1	Gene:	sr / 42162	FlyBaseID:	FBgn0003499	Length:	1271	Species:	Drosophila melanogaster

Alignment Length:	317	Identity:	88/317 - (27%)
Similarity:	135/317 - (42%)	Gaps:	85/317 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    91 QQQQQLYASSGVSKLPFSPFFAASPFFFTYRRISGSGSGNGTGSVSVKQEDNNNSCSYNNGSSSG 155
            |||||...::|.:..|:....||:.....:..:.|...  ....:.:||...:.:     |:|:|
  Fly   812 QQQQQQQQAAGAAPSPYDDGRAAAAAAAQHAELLGLTM--DCTPLLLKQPPPSYA-----GASAG 869

  Fly   156 --GAGSAANS------MQDY---ESKFSLLSLFKNPYKFAGGDGQASR------------KTSPT 197
              |.|...:|      .|.|   :.|:..|.   :|..:|....|..:            ...||
  Fly   870 FPGLGDLHSSHEQQLQQQQYVRSQPKYQWLD---SPADYAQQQQQVQQVQQQQQQQQTLVLPGPT 931

  Fly   198 GGSSKPLASNSS-----PSWKSYAGSGSPHAALNPAFGGMGRGATRKDNSSFSGINFGGGGSAFG 257
            ..:|   :||::     |..::|..       :.|:..|.|          :||   |.|||:..
  Fly   932 SSAS---SSNAALGVLIPKQENYPD-------MQPSSNGTG----------YSG---GSGGSSAA 973

  Fly   258 FTTSSDSMAN----GGYN-DLSKNRKVHKCDTEGCDKVYTKSS------HLKAHK------RTHT 305
            ...::.:.|.    ..|: ..||..::       ..:||.:|:      .:|..|      :|..
  Fly   974 AAAAAAAAAAAVQLAEYSPSTSKGHEI-------LSQVYQQSTVPLKLVPVKPRKYPNRPSKTPV 1031

  Fly   306 GEKPYVCTWEGCIWRFARSDELTRHYRKHTGVKPFRCQLCTRSFSRSDHLSLHMRRH 362
            .|:||.|..|.|..||:||||||||.|.|||.|||:|::|.|||||||||:.|:|.|
  Fly  1032 HERPYACPVENCDRRFSRSDELTRHIRIHTGQKPFQCRICMRSFSRSDHLTTHIRTH 1088

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42741	NP_611747.2	COG5048	<273..>352	CDD:227381	37/90 (41%)
		zf-C2H2	280..304	CDD:278523	5/35 (14%)
		C2H2 Zn finger	282..304	CDD:275368	5/33 (15%)
		zf-H2C2_2	296..>313	CDD:290200	6/22 (27%)
		C2H2 Zn finger	312..334	CDD:275368	14/21 (67%)
		zf-H2C2_2	326..351	CDD:290200	17/24 (71%)
		C2H2 Zn finger	342..362	CDD:275368	13/19 (68%)
sr	NP_001262693.1	zf-C2H2	1036..1060	CDD:278523	15/23 (65%)
		C2H2 Zn finger	1038..1060	CDD:275368	14/21 (67%)
		zf-H2C2_2	1052..1077	CDD:290200	17/24 (71%)
		C2H2 Zn finger	1068..1088	CDD:275368	13/19 (68%)
		zf-H2C2_2	1080..1105	CDD:290200	5/9 (56%)
		C2H2 Zn finger	1096..1116	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR23235
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010