DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42741 and hkb

DIOPT Version :9

Sequence 1:	NP_611747.2	Gene:	CG42741 / 37654	FlyBaseID:	FBgn0261705	Length:	362	Species:	Drosophila melanogaster
Sequence 2:	NP_524221.1	Gene:	hkb / 40549	FlyBaseID:	FBgn0261434	Length:	297	Species:	Drosophila melanogaster

Alignment Length:	264	Identity:	69/264 - (26%)
Similarity:	109/264 - (41%)	Gaps:	63/264 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   134 SVSVKQEDNNNS----CSYNNGSSSGGAGSAANSMQD-YE-----SKFSLLS----------LFK 178
            ::::|.|..::|    |..:..|:|..|.|::||.:. ||     |.::..|          :|.
  Fly    40 AITIKTELASSSFGHDCDGDFSSASSSASSSSNSSKSCYEEALNHSSYTRTSTPLLDAAPHPVFS 104

  Fly   179 NPYKFAGGDGQASRKTSPTGGSSKPLASNSSPSWKS----------YAGSGSPHAALN-----PA 228
            :|            ::||....:...||.:.|:..:          ||.:.:..||.:     |.
  Fly   105 HP------------QSSPLDTHAAATASLAPPNQHAPFLSAASDLYYAAAAAAAAAASTPTAVPG 157

  Fly   229 FGGMGRGATRKDNSSFSGINFGGGGSAFGFTTSSDSMANGGYNDLSKNRKVHKCDTEGCDKVYTK 293
            ||             ......|.....:....:.|:... ..|...:..|..||  ..||..::.
  Fly   158 FG-------------MDPFTMGLMEQEYARVMAEDAQLK-ALNSRKQRPKKFKC--PNCDVAFSN 206

  Fly   294 SSHLKAHKRTHTGEKPYVCTWEGCIWRFARSDELTRHYRKHTGVKPFRCQLCTRSFSRSDHLSLH 358
            :..||.|.|.||||:|:.|....|...|.|::|||||.|.|||::|:.|..|.:.|.|.|||..|
  Fly   207 NGQLKGHIRIHTGERPFKCDVNTCGKTFTRNEELTRHKRIHTGLRPYPCSACGKKFGRRDHLKKH 271

  Fly   359 MRRH 362
            |:.|
  Fly   272 MKTH 275

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42741	NP_611747.2	COG5048	<273..>352	CDD:227381	31/78 (40%)
		zf-C2H2	280..304	CDD:278523	8/23 (35%)
		C2H2 Zn finger	282..304	CDD:275368	7/21 (33%)
		zf-H2C2_2	296..>313	CDD:290200	9/16 (56%)
		C2H2 Zn finger	312..334	CDD:275368	10/21 (48%)
		zf-H2C2_2	326..351	CDD:290200	13/24 (54%)
		C2H2 Zn finger	342..362	CDD:275368	9/19 (47%)
hkb	NP_524221.1	COG5048	195..>261	CDD:227381	29/67 (43%)
		zf-C2H2	195..217	CDD:278523	8/23 (35%)
		C2H2 Zn finger	197..217	CDD:275368	7/21 (33%)
		zf-H2C2_2	210..236	CDD:290200	12/25 (48%)
		C2H2 Zn finger	225..247	CDD:275368	10/21 (48%)
		zf-H2C2_2	239..264	CDD:290200	13/24 (54%)
		C2H2 Zn finger	255..275	CDD:275368	9/19 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR23235
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010