Protein Alignment CG42741 and Sp8

DIOPT Version :10

• Sequence 1: NP_611747.2
• Gene: CG42741 / 37654
• FlyBaseID: FBgn0261705
• Length: 362
• Species: Drosophila melanogaster
• Sequence 2: NP_001366308.1
• Gene: Sp8 / 320145
• MGIID: 2443471
• Length: 504
• Species: Mus musculus
• Alignment Length: 477
• Identity: 136/477 - (28%)
• Similarity: 178/477 - (37%)
• Gaps: 153/477 - (32%)

  Fly     7 LGSDPLSAKEAE----GPPVQVEPVDLSLRS----------PRASTSH-------GSSSSSYKFS 50
            |||.||:...|.    |.| ...|..||..|          .|:|:|.       |||.||:..|
Mouse    12 LGSTPLAMLAATCNKIGSP-SPSPSSLSDSSSSFGKGFHPWKRSSSSSSGSCNVVGSSLSSFGVS 75

  Fly    51 SANKAVGYSNGKP-------------------GGSSGSS--------------------SSSGF- 75
            .|::..|.|:...                   |||.|||                    |||.|
Mouse    76 GASRNGGSSSAAAAAAAAAAAAAALVSDSFSCGGSPGSSAFSLTSSSAAAAAAAAAAAASSSPFA 140

  Fly    76 -------------GAGSAGSSSLGAFAAQQQQQLYASSGVSKL------------------PFSP 109
                         |:|..|....|...|..|...:....:||:                  |:..
Mouse   141 NDYSVFQAPGVSGGSGGGGGGGGGGSGAHSQDSSHQPVFISKVHTSVDGLQGIYPRVGMAHPYES 205

  Fly   110 FFAAS-PFFFTYRRISGSGSGN----GTGSVSVKQEDNNNSCSYNNGSSSGGAGSAANSMQD--- 166
            :|..| |.......:..:|:.:    |.|.:.|:   |.|..:...||....||....|:..
Mouse   206 WFKPSHPGLGAAADVGSAGASSWWDVGAGWIDVQ---NPNGAAALPGSLHPAAGGLQTSLHSPLG 267

  Fly   167 -YESKFSLLSLFKNPYKFAGGDGQASRKTSPTG----GSSKPLASNSSP--SWKSYAGSGSPHAA 224
             |.|.:|.||      ..|...|.:|...||.|    ...||:...|.|  :....||:||...:
Mouse   268 GYNSDYSGLS------HSAFSSGASSHLLSPAGQHLMDGFKPVLPGSYPDSAPSPLAGAGSSMLS 326

  Fly   225 LNPA--FGGMGRGATRKDNSSFSG------------INFGGGGSAFGFTTSSDSMANGGYNDLSK 275
            ..||  .||..|.:.|:    :||            ...|..|::.                  :
Mouse   327 AGPAAQLGGSPRSSARR----YSGRATCDCPNCQEAERLGPAGASL------------------R 369

  Fly   276 NRKVHKCDTEGCDKVYTKSSHLKAHKRTHTGEKPYVCTWEGCIWRFARSDELTRHYRKHTGVKPF 340
            .:.:|.|...||.|||.|:||||||.|.||||:|:||.|..|..||.|||||.||.|.|||.|.|
Mouse   370 RKGLHSCHIPGCGKVYGKTSHLKAHLRWHTGERPFVCNWLFCGKRFTRSDELQRHLRTHTGEKRF 434

  Fly   341 RCQLCTRSFSRSDHLSLHMRRH 362
            .|.:|.:.|.||||||.|::.|
Mouse   435 ACPVCNKRFMRSDHLSKHVKTH 456

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42741	NP_611747.2	COG5048	<273..>352	CDD:227381	42/78 (54%)
		C2H2 Zn finger	282..304	CDD:275368	14/21 (67%)
		C2H2 Zn finger	312..334	CDD:275368	13/21 (62%)
		zf-H2C2_2	326..351	CDD:463886	13/24 (54%)
		C2H2 Zn finger	342..362	CDD:275368	10/19 (53%)
Sp8	NP_001366308.1	SP8_N	19..375	CDD:411690	81/387 (21%)
		C2H2 Zn finger	379..398	CDD:275368	13/18 (72%)
		zf-H2C2_2	390..417	CDD:463886	17/26 (65%)
		C2H2 Zn finger	406..428	CDD:275368	13/21 (62%)
		zf-H2C2_2	420..443	CDD:463886	12/22 (55%)
		zf-C2H2	434..456	CDD:395048	11/21 (52%)
		C2H2 Zn finger	436..456	CDD:275368	10/19 (53%)