Protein Alignment CG42741 and Klf2

DIOPT Version :10

• Sequence 1: NP_611747.2
• Gene: CG42741 / 37654
• FlyBaseID: FBgn0261705
• Length: 362
• Species: Drosophila melanogaster
• Sequence 2: NP_001007685.1
• Gene: Klf2 / 306330
• RGDID: 1359220
• Length: 351
• Species: Rattus norvegicus
• Alignment Length: 401
• Identity: 114/401 - (28%)
• Similarity: 144/401 - (35%)
• Gaps: 137/401 - (34%)

  Fly     3 FMNGLGSDPLSAKEAEGPPVQVEPVDLSLRSPRASTSHGSSSSSYKFSSANKAVGYSNGKPGGSS 67
            |:..:|.|.|.|:....||.|..|.......|.|...:|:                    |....
  Rat    46 FILSMGLDGLGAENPPEPPPQPPPPAFYYPEPGAPPPYGT--------------------PAAGL 90

  Fly    68 GSSSSSGFGAGSAGSSSLGAFAAQQQQQLYASSGVSKLPFSPFFAASPFFFTYRRISGSG----S 128
            |:...........|.:..|.|       |.|..|       ....|.|     ..:.|.|    :
  Rat    91 GTELLRPDLDAPQGPALHGRF-------LLAPPG-------RLVKAEP-----PEVDGGGYGCAA 136

  Fly   129 GNGTGSVSVKQEDNNNSCSYNNGSSSGGAGSAANSMQDYESKFSLLSLFKNPYKFAGGDGQASRK 193
            |...|...:|.|              |..|:....|:                      |.|.|.
  Rat   137 GLARGPRGLKLE--------------GALGATGACMR----------------------GPAGRP 165

  Fly   194 TSPTGGSSKPLASNSSPSWKSYAGSGSPHAALNPAFGGMGRGATRKDNSSFSGINFGGGGSAFGF 258
            ..|:  .:.||:.:..|.    ..:..|.....|.||              .|.:|||.|.|..:
  Rat   166 PPPS--DTPPLSPDGPPR----LPAPGPRNPFPPPFG--------------PGPSFGGPGPALHY 210

  Fly   259 TTSSDSMANGGYNDLS-------------------------------------KNRKVHKCDTEG 286
            ...:.. |.|.::|.:                                     |....|.|....
  Rat   211 GPPAPG-AFGLFDDAAAALGLAPPATRGLLTPPSSPLELLEAKPKRGRRSWPRKRAATHTCSYTN 274

  Fly   287 CDKVYTKSSHLKAHKRTHTGEKPYVCTWEGCIWRFARSDELTRHYRKHTGVKPFRCQLCTRSFSR 351
            |.|.||||||||||.|||||||||.|.|:||.|:||||||||||||||||.:||:|.||.|:|||
  Rat   275 CGKTYTKSSHLKAHLRTHTGEKPYHCNWDGCGWKFARSDELTRHYRKHTGHRPFQCHLCDRAFSR 339

  Fly   352 SDHLSLHMRRH 362
            ||||:|||:||
  Rat   340 SDHLALHMKRH 350

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42741	NP_611747.2	COG5048	<273..>352	CDD:227381	53/115 (46%)
		C2H2 Zn finger	282..304	CDD:275368	14/21 (67%)
		C2H2 Zn finger	312..334	CDD:275368	17/21 (81%)
		zf-H2C2_2	326..351	CDD:463886	18/24 (75%)
		C2H2 Zn finger	342..362	CDD:275368	14/19 (74%)
Klf2	NP_001007685.1	KLF2_N	4..268	CDD:409229	52/317 (16%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	20..110		15/83 (18%)
		9aaTAD. /evidence=ECO:0000250|UniProtKB:Q9Y5W3	42..50		1/3 (33%)
		Interaction with WWP1. /evidence=ECO:0000250	110..264		35/229 (15%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	156..209		18/94 (19%)
		COG5048	<266..346	CDD:227381	57/79 (72%)
		C2H2 Zn finger	270..292	CDD:275368	14/21 (67%)
		C2H2 Zn finger	300..322	CDD:275368	17/21 (81%)
		C2H2 Zn finger	330..350	CDD:275368	14/19 (74%)