DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42741 and klf6a

DIOPT Version :9

Sequence 1:	NP_611747.2	Gene:	CG42741 / 37654	FlyBaseID:	FBgn0261705	Length:	362	Species:	Drosophila melanogaster
Sequence 2:	NP_958869.2	Gene:	klf6a / 280650	ZFINID:	ZDB-GENE-021115-9	Length:	283	Species:	Danio rerio

Alignment Length:	273	Identity:	109/273 - (39%)
Similarity:	139/273 - (50%)	Gaps:	48/273 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   105 LPFSPFFAASPFFFTYRR-------ISGSGSGNGTGSVSVKQEDNNNSCSY--NNGSSSGGAGSA 160
            |...|:.:||...|..:.       ::....|:|.||:...:||:|..|..  .|..:|..:..|
Zfish    43 LQSEPYVSASDLKFEGQEDLWSKLILACGDKGDGNGSLPSVKEDDNQDCQILETNSMNSDASSEA 107

  Fly   161 ANSMQDYESKFSLLSLFKNPYKFAGGDGQASRKTSPTG-GSSKPLAS---NSSPSWKSYAGSGSP 221
            ::|                           |.:.|||. .:|.||.|   .|:....|...|..|
Zfish   108 SDS---------------------------SEELSPTHIFTSNPLGSVLTESAHHLSSSIISTPP 145

  Fly   222 HAALNPAFGGMGR--GATRKDNSSFSGINFGGGGSAFGFTTSSDSMANGGYNDLSKNRKVHKCDT 284
            .:...|...|:.:  |:|:.|......|...|.|.|...||:      ||.......|:||:|..
Zfish   146 SSPEMPQEPGVPQVWGSTQTDLHIPVKIRQNGLGKALDKTTT------GGDASPDGRRRVHRCHF 204

  Fly   285 EGCDKVYTKSSHLKAHKRTHTGEKPYVCTWEGCIWRFARSDELTRHYRKHTGVKPFRCQLCTRSF 349
            .||.||||||||||||:|||||||||.|:||||.||||||||||||:|||||.|||:|..|.|.|
Zfish   205 NGCRKVYTKSSHLKAHQRTHTGEKPYRCSWEGCEWRFARSDELTRHFRKHTGAKPFKCSHCDRCF 269

  Fly   350 SRSDHLSLHMRRH 362
            ||||||:|||:||
Zfish   270 SRSDHLALHMKRH 282

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42741	NP_611747.2	COG5048	<273..>352	CDD:227381	57/78 (73%)
		zf-C2H2	280..304	CDD:278523	17/23 (74%)
		C2H2 Zn finger	282..304	CDD:275368	16/21 (76%)
		zf-H2C2_2	296..>313	CDD:290200	14/16 (88%)
		C2H2 Zn finger	312..334	CDD:275368	18/21 (86%)
		zf-H2C2_2	326..351	CDD:290200	17/24 (71%)
		C2H2 Zn finger	342..362	CDD:275368	13/19 (68%)
klf6a	NP_958869.2	COG5048	171..>265	CDD:227381	61/99 (62%)
		C2H2 Zn finger	205..224	CDD:275368	15/18 (83%)
		C2H2 Zn finger	232..254	CDD:275368	18/21 (86%)
		zf-H2C2_2	246..271	CDD:290200	17/24 (71%)
		C2H2 Zn finger	262..282	CDD:275368	13/19 (68%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D416605at33208
OrthoFinder	1	1.000	-	-		FOG0000436
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23235
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	4.020