DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42741 and luna

DIOPT Version :9

Sequence 1:	NP_611747.2	Gene:	CG42741 / 37654	FlyBaseID:	FBgn0261705	Length:	362	Species:	Drosophila melanogaster
Sequence 2:	NP_001260879.1	Gene:	luna / 2768719	FlyBaseID:	FBgn0040765	Length:	570	Species:	Drosophila melanogaster

Alignment Length:	332	Identity:	118/332 - (35%)
Similarity:	154/332 - (46%)	Gaps:	108/332 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    50 SSANKAVGYSN---GKPGGSSGSSSSSGFGAGSAGSSSLGAFAAQQQQQLYASSGVSKLPFSPFF 111
            |.:.:|:|:||   ..|..||.|||:|...:.|:.||| .:.:....|..:     |.:|.|
  Fly   327 SISPQALGHSNIGSNSPKSSSSSSSNSSNSSSSSHSSS-SSISGSSDQPTH-----SNIPRS--- 382

  Fly   112 AASPFFFTYRRISGSGSGNGTGSVS---VKQEDNN-------------NSCSYNNGSSSGGAGSA 160
                   |..|::.:....|...:|   |.|..||             ||.|.|:.|:|..:.::
  Fly   383 -------TIVRLTTANGKPGAAGISLARVIQMQNNGNANVAAVLSAAANSGSSNSNSNSSSSNTS 440

  Fly   161 ANSMQDYESKFSLLSLFKNPYKFAGGDGQASRKTSPTGGSSKPLASNSSPSWKSYAGSGSPHAAL 225
            :||:.....:..:||             |.|.|::  .|||||    ..|  :.:....||.|
  Fly   441 SNSINTATPQQQVLS-------------QRSEKSA--NGSSKP----HHP--RQHHSDHSPDA-- 482

  Fly   226 NPAFGGMGRGATRKDNSSFSGINFGGGGSAFGFTTSSDSMANGGYNDLSKNRKVHKCDTEGCDKV 290
                                                              .|::|||...||.||
  Fly   483 --------------------------------------------------KRRIHKCQFLGCKKV 497

  Fly   291 YTKSSHLKAHKRTHTGEKPYVCTWEGCIWRFARSDELTRHYRKHTGVKPFRCQLCTRSFSRSDHL 355
            ||||||||||:|||||||||.|:||||.||||||||||||||||||.|||:|:.|.|.|||||||
  Fly   498 YTKSSHLKAHQRTHTGEKPYKCSWEGCEWRFARSDELTRHYRKHTGAKPFKCRNCDRCFSRSDHL 562

  Fly   356 SLHMRRH 362
            :|||:||
  Fly   563 ALHMKRH 569

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42741	NP_611747.2	COG5048	<273..>352	CDD:227381	58/78 (74%)
		zf-C2H2	280..304	CDD:278523	18/23 (78%)
		C2H2 Zn finger	282..304	CDD:275368	16/21 (76%)
		zf-H2C2_2	296..>313	CDD:290200	14/16 (88%)
		C2H2 Zn finger	312..334	CDD:275368	19/21 (90%)
		zf-H2C2_2	326..351	CDD:290200	18/24 (75%)
		C2H2 Zn finger	342..362	CDD:275368	13/19 (68%)
luna	NP_001260879.1	COG5048	<455..>559	CDD:227381	71/176 (40%)
		C2H2 Zn finger	489..511	CDD:275368	16/21 (76%)
		zf-H2C2_2	503..>519	CDD:290200	14/15 (93%)
		C2H2 Zn finger	519..541	CDD:275368	19/21 (90%)
		zf-H2C2_2	533..558	CDD:290200	18/24 (75%)
		C2H2 Zn finger	549..569	CDD:275368	13/19 (68%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45455435
Domainoid	1	1.000	40	1.000	Domainoid score	I3723
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D416605at33208
OrthoFinder	1	1.000	-	-		FOG0000436
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR23235
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.950