Protein Alignment CG42741 and Sp4

DIOPT Version :10

• Sequence 1: NP_611747.2
• Gene: CG42741 / 37654
• FlyBaseID: FBgn0261705
• Length: 362
• Species: Drosophila melanogaster
• Sequence 2: NP_033265.4
• Gene: Sp4 / 20688
• MGIID: 107595
• Length: 782
• Species: Mus musculus
• Alignment Length: 448
• Identity: 112/448 - (25%)
• Similarity: 161/448 - (35%)
• Gaps: 127/448 - (28%)

  Fly    20 PPVQVEPVDLSLRSPRASTSHGSSSSSYKFSSANKAVGYSNGKPGGSSGSSS------------- 71
            |.....|......||.:||:..:::|:...||.........|:...:|.|||
Mouse   302 PTTSTAPASTMPESPSSSTTCTTTASTTLTSSDTLVSSADTGQYASTSASSSERTIEEPQTPAAT 366

  Fly    72 -----------SSGFGAGSAGSSSL------GAFAAQQQQ-----------------QLYASSGV 102
                       |:|.......|:||      |....||.|                 ||.:...:
Mouse   367 ESEAQSSSQLQSNGIQNAQDQSNSLQQVQIVGQPILQQIQIQQPQQQIIQAIPPQSFQLQSGQTI 431

  Fly   103 SKLPFSP-----FFAASPFFFTYRRISGSGSGN-GTGSVSVKQEDNNNSCSYNNGSSSGGAGSAA 161
            ..:...|     ..|.:|.....|..:.:.||. ...:|.|:...:.::....|         |.
Mouse   432 QTIQQQPLQNVQLQAVNPTQVLIRAPTLTPSGQISWQTVQVQNIQSLSNLQVQN---------AG 487

  Fly   162 NSMQDYESKFSLLSLFKNPYKFAGGDGQASRKTSPTGGSSKPLASN-----SSPSWKSY------ 215
            .|.|          |...|...:||...|  :.:|...:..|:..|     |.|:.::.
Mouse   488 LSQQ----------LTITPVSSSGGTTLA--QIAPVAVAGAPITLNTAQLASVPNLQTVSVANLG 540

  Fly   216 -AG---SGSPHAALNPAFGGMGRGATRKDNSSFSGINFGGGGSA------------------FGF 258
             ||   .|.|....:.|....|:...:...::.:.:....||.|                  .|.
Mouse   541 AAGVQVQGVPVTITSVAGQQQGQDGVKVQQATIAPVTVAVGGIANATIGAVSPDQLTQVHLQQGQ 605

  Fly   259 TTSSDSMANG-------------------GYNDLSKNRKVHKCDTEGCDKVYTKSSHLKAHKRTH 304
            .||...:..|                   |.::..| :|.|.|..|||.|||.|:|||:||.|.|
Mouse   606 QTSDAEVQPGKRLRRVACSCPNCREGEGRGSSEPGK-KKQHVCHIEGCGKVYGKTSHLRAHLRWH 669

  Fly   305 TGEKPYVCTWEGCIWRFARSDELTRHYRKHTGVKPFRCQLCTRSFSRSDHLSLHMRRH 362
            |||:|::|.|..|..||.|||||.||.|.|||.|.|.|..|::.|.||||||.|::.|
Mouse   670 TGERPFICNWMFCGKRFTRSDELQRHRRTHTGEKRFECPECSKRFMRSDHLSKHVKTH 727

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42741	NP_611747.2	COG5048	<273..>352	CDD:227381	43/78 (55%)
		C2H2 Zn finger	282..304	CDD:275368	14/21 (67%)
		C2H2 Zn finger	312..334	CDD:275368	13/21 (62%)
		zf-H2C2_2	326..351	CDD:463886	13/24 (54%)
		C2H2 Zn finger	342..362	CDD:275368	10/19 (53%)
Sp4	NP_033265.4	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..48
		SP4_N	30..646	CDD:411773	63/365 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	107..148
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	275..385		16/82 (20%)
		9aaTAD, inactive. /evidence=ECO:0000250|UniProtKB:Q02446	465..473		1/7 (14%)
		zf-C2H2	645..669	CDD:395048	15/23 (65%)
		C2H2 Zn finger	647..669	CDD:275368	14/21 (67%)
		zf-C2H2	675..699	CDD:395048	13/23 (57%)
		C2H2 Zn finger	677..699	CDD:275368	13/21 (62%)
		zf-H2C2_2	691..714	CDD:463886	12/22 (55%)
		zf-C2H2	705..727	CDD:395048	11/21 (52%)
		C2H2 Zn finger	707..727	CDD:275368	10/19 (53%)