DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG42741 and Klf2

DIOPT Version :9

Sequence 1:NP_611747.2 Gene:CG42741 / 37654 FlyBaseID:FBgn0261705 Length:362 Species:Drosophila melanogaster
Sequence 2:NP_032478.2 Gene:Klf2 / 16598 MGIID:1342772 Length:354 Species:Mus musculus


Alignment Length:214 Identity:86/214 - (40%)
Similarity:98/214 - (45%) Gaps:59/214 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly   188 GQASRKTSPTGGSSKPLASNSSPSWKSYAGSGSPHAALNPAFGGMGRGATRKDNSSFSGINFGGG 252
            |.|.|...|.  .:.||    ||.......:..|.....|.||              .|.:|||.
Mouse   160 GPAGRPPPPP--DTPPL----SPDGPLRIPASGPRNPFPPPFG--------------PGPSFGGP 204

  Fly   253 G----------SAFGFTTSSDSMA-----------------------------NGGYNDLSKNRK 278
            |          .|||....:.:.|                             .|..:...|...
Mouse   205 GPALHYGPPAPGAFGLFEDAAAAAAALGLAPPATRGLLTPPSSPLELLEAKPKRGRRSWPRKRAA 269

  Fly   279 VHKCDTEGCDKVYTKSSHLKAHKRTHTGEKPYVCTWEGCIWRFARSDELTRHYRKHTGVKPFRCQ 343
            .|.|....|.|.||||||||||.|||||||||.|.||||.|:||||||||||||||||.:||:|.
Mouse   270 THTCSYTNCGKTYTKSSHLKAHLRTHTGEKPYHCNWEGCGWKFARSDELTRHYRKHTGHRPFQCH 334

  Fly   344 LCTRSFSRSDHLSLHMRRH 362
            ||.|:|||||||:|||:||
Mouse   335 LCDRAFSRSDHLALHMKRH 353

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG42741NP_611747.2 COG5048 <273..>352 CDD:227381 54/78 (69%)
zf-C2H2 280..304 CDD:278523 15/23 (65%)
C2H2 Zn finger 282..304 CDD:275368 14/21 (67%)
zf-H2C2_2 296..>313 CDD:290200 14/16 (88%)
C2H2 Zn finger 312..334 CDD:275368 18/21 (86%)
zf-H2C2_2 326..351 CDD:290200 18/24 (75%)
C2H2 Zn finger 342..362 CDD:275368 14/19 (74%)
Klf2NP_032478.2 9aaTAD. /evidence=ECO:0000250|UniProtKB:Q9Y5W3 42..50
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 52..111
Interaction with WWP1 110..267 22/126 (17%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 145..208 17/67 (25%)
zf-C2H2 271..295 CDD:278523 15/23 (65%)
C2H2 Zn finger 273..295 CDD:275368 14/21 (67%)
COG5048 <276..>353 CDD:227381 59/76 (78%)
zf-C2H2 301..325 CDD:278523 19/23 (83%)
C2H2 Zn finger 303..325 CDD:275368 18/21 (86%)
zf-H2C2_2 317..342 CDD:290200 18/24 (75%)
C2H2 Zn finger 333..353 CDD:275368 14/19 (74%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR23235
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
22.010

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