Protein Alignment CG42741 and Klf12

DIOPT Version :10

• Sequence 1: NP_611747.2
• Gene: CG42741 / 37654
• FlyBaseID: FBgn0261705
• Length: 362
• Species: Drosophila melanogaster
• Sequence 2: NP_034766.2
• Gene: Klf12 / 16597
• MGIID: 1333796
• Length: 402
• Species: Mus musculus
• Alignment Length: 398
• Identity: 136/398 - (34%)
• Similarity: 175/398 - (43%)
• Gaps: 99/398 - (24%)

  Fly    11 PLSAKEAEGPP-----------VQVEPVDLSLRSPRASTSHGSSS-----SSYKFSSANKAVGYS 59
            ||.....:|.|           .|.||||||:...|.|.:..|||     :|....|:......|
Mouse    55 PLLLNNVKGEPPEDSLPVDHFQTQTEPVDLSINKARTSPTAASSSPVSMTASASSPSSTSTSSSS 119

  Fly    60 NGKPGG--------SSGSSSSSGFGAGS--AGSSSLGAFAAQQQQQLYASSGVSKLPFSPFFAAS 114
            :.:|..        ||.||||:....|.  |.:|.:|.     ||.|:....|.  |.||....|
Mouse   120 SSRPASSPTVITSVSSASSSSTVLSPGPLVASASGVGG-----QQFLHIIHPVP--PSSPMNLQS 177

  Fly   115 ----------------PFFFTYRRISGSGSGNGTGSVSVKQEDNNNSCSYNNGSSSGGAGSAANS 163
                            |..:|  .:...|:.|.|..|.:.::          |.|.|.|......
Mouse   178 NKLSHVHRIPVVVQSVPVVYT--AVRSPGNVNNTIVVPLLED----------GRSHGKAQMEPRG 230

  Fly   164 MQDYESKFSLLSLFKNPYKFAGGDGQASRKT----SPTGGSSKPLASNSSPSWKSYAGSGSPHAA 224
            :...:||..            ..|......|    :.||.::..:|....              .
Mouse   231 LSPRQSKSD------------SDDDDLPNVTLDSVNETGSTALSIARAVQ--------------E 269

  Fly   225 LNPAFGGMGRGATRKDNSSFSGINFGGGGSAFGFTTSSDSMANGGYNDLSKNRKVHKCDTEGCDK 289
            ::|:.....|| .|.:|..|:       .|...|:..|........:..|:.|::|:||.|||:|
Mouse   270 VHPSPVSRVRG-NRMNNQKFA-------CSISPFSIESTRRQRRSESPDSRKRRIHRCDFEGCNK 326

  Fly   290 VYTKSSHLKAHKRTHTGEKPYVCTWEGCIWRFARSDELTRHYRKHTGVKPFRCQLCTRSFSRSDH 354
            |||||||||||:|||||||||.||||||.|:||||||||||||||||||||:|..|.||||||||
Mouse   327 VYTKSSHLKAHRRTHTGEKPYKCTWEGCTWKFARSDELTRHYRKHTGVKPFKCADCDRSFSRSDH 391

  Fly   355 LSLHMRRH 362
            |:||.|||
Mouse   392 LALHRRRH 399

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42741	NP_611747.2	COG5048	<273..>352	CDD:227381	62/78 (79%)
		C2H2 Zn finger	282..304	CDD:275368	18/21 (86%)
		C2H2 Zn finger	312..334	CDD:275368	19/21 (90%)
		zf-H2C2_2	326..351	CDD:463886	20/24 (83%)
		C2H2 Zn finger	342..362	CDD:275368	14/19 (74%)
Klf12	NP_034766.2	KLF12_N	27..224	CDD:410608	47/187 (25%)
		9aaTAD, inactive. /evidence=ECO:0000250|UniProtKB:Q9Y4X4	80..88		6/7 (86%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	81..144		20/62 (32%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	219..254		7/46 (15%)
		COG5048	<225..401	CDD:227381	88/209 (42%)
		C2H2 Zn finger	319..341	CDD:275368	18/21 (86%)
		C2H2 Zn finger	349..371	CDD:275368	19/21 (90%)
		zf-H2C2_2	363..388	CDD:463886	20/24 (83%)
		C2H2 Zn finger	379..399	CDD:275368	14/19 (74%)