DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG42741 and Klf1

DIOPT Version :9

Sequence 1:NP_611747.2 Gene:CG42741 / 37654 FlyBaseID:FBgn0261705 Length:362 Species:Drosophila melanogaster
Sequence 2:NP_034765.3 Gene:Klf1 / 16596 MGIID:1342771 Length:358 Species:Mus musculus


Alignment Length:335 Identity:119/335 - (35%)
Similarity:147/335 - (43%) Gaps:114/335 - (34%)


- Green bases have known domain annotations that are detailed below.


  Fly   125 GSGSGNGTG---SVSVKQEDNNN-------SCSYN--------NGSSSGGA------GSAANSMQ 165
            |.|..|.||   .||:|.||.:.       :|:::        .||.|.|.      ..:...:.
Mouse    40 GPGPPNPTGPSHHVSLKSEDPSGEDDERDVTCAWDPDLFLTNFPGSESPGTSRTCALAPSVGPVA 104

  Fly   166 DYESKFSLLSLFKNPYKFAGGDGQASRKTSPTGG---------SSKP--------------LASN 207
            .:|...||.:       :|||.|..   |.|.|.         :.:|              ||..
Mouse   105 QFEPPESLGA-------YAGGPGLV---TGPLGSEEHTSWAHPTPRPPAPEPFVAPALAPGLAPK 159

  Fly   208 SSPSWK-SYAGS----------------GSPHA------ALNPA---------FGGM---GRGAT 237
            :.||:. |.|||                |:|:.      ||.||         |.|:   ..|.|
Mouse   160 AQPSYSDSRAGSVGGFFPRAGLAVPAAPGAPYGLLSGYPALYPAPQYQGHFQLFRGLAAPSAGPT 224

  Fly   238 RKDNSSFSGINFGGGGSAFGFTTSSDSMANGGYNDLS---------------KNRKVHKCDTEGC 287
            ...    |.:|..|.|:.   .|...:.|..|...||               |.:..|.|..|||
Mouse   225 APP----SFLNCLGPGTV---ATELGATAIAGDAGLSPGTAPPKRSRRTLAPKRQAAHTCGHEGC 282

  Fly   288 DKVYTKSSHLKAHKRTHTGEKPYVCTWEGCIWRFARSDELTRHYRKHTGVKPFRCQLCTRSFSRS 352
            .|.||||||||||.|||||||||.|:|:||.||||||||||||||||||.:||.|.||.|:||||
Mouse   283 GKSYTKSSHLKAHLRTHTGEKPYACSWDGCDWRFARSDELTRHYRKHTGHRPFCCGLCPRAFSRS 347

  Fly   353 DHLSLHMRRH 362
            |||:|||:||
Mouse   348 DHLALHMKRH 357

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG42741NP_611747.2 COG5048 <273..>352 CDD:227381 58/93 (62%)
zf-C2H2 280..304 CDD:278523 17/23 (74%)
C2H2 Zn finger 282..304 CDD:275368 16/21 (76%)
zf-H2C2_2 296..>313 CDD:290200 14/16 (88%)
C2H2 Zn finger 312..334 CDD:275368 18/21 (86%)
zf-H2C2_2 326..351 CDD:290200 18/24 (75%)
C2H2 Zn finger 342..362 CDD:275368 14/19 (74%)
Klf1NP_034765.3 EKLF_TAD1 22..>39 CDD:318931
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 35..69 10/28 (36%)
EKLF_TAD2 63..85 CDD:318932 1/21 (5%)
9aaTAD. /evidence=ECO:0000250|UniProtKB:Q13351 71..79 1/7 (14%)
COG5048 <279..>357 CDD:227381 61/77 (79%)
C2H2 Zn finger 280..299 CDD:275368 15/18 (83%)
C2H2 Zn finger 307..329 CDD:275368 18/21 (86%)
C2H2 Zn finger 337..357 CDD:275368 14/19 (74%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR23235
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
33.010

Return to query results.
Submit another query.