Protein Alignment CG42741 and KLF14

DIOPT Version :10

• Sequence 1: NP_611747.2
• Gene: CG42741 / 37654
• FlyBaseID: FBgn0261705
• Length: 362
• Species: Drosophila melanogaster
• Sequence 2: NP_619638.2
• Gene: KLF14 / 136259
• HGNCID: 23025
• Length: 323
• Species: Homo sapiens
• Alignment Length: 297
• Identity: 99/297 - (33%)
• Similarity: 128/297 - (43%)
• Gaps: 63/297 - (21%)

  Fly    76 GAGSAGSSSLGAFAAQQQQQL-----YASSGVSKLPFSPFFAASPFFFTYRRISGSGSGNG---- 131
            |||.|..|.:|  ||..:..|     ...:.|.:||..|  |.||           |:|..
Human    34 GAGGAAGSEVG--AAPPESALPGPGPPGPASVPQLPQVP--APSP-----------GAGGAAPHL 83

  Fly   132 -TGSVSVKQEDNNNSCSYNNGSSSGGAGSAANSMQDYESKFSLLSLFKNPYKFAGGDGQASRKTS 195
             ..||......::...|:.|   ||.|..|::...|     .:....:.|.........|:...:
Human    84 LAASVWADLRGSSGEGSWEN---SGEAPRASSGFSD-----PIPCSVQTPCSELAPASGAAAVCA 140

  Fly   196 PTGGSSKPLASNSSPSWKSYAGSGSPHAALNPAFGGMGRGATRKDNSSFSGINFGGGGSAFGFTT 260
            |...|..| |..|:|     |..|:|.|:     ||                 |.||....|...
Human   141 PESSSDAP-AVPSAP-----AAPGAPAAS-----GG-----------------FSGGALGAGPAP 177

  Fly   261 SSDSMANGGYNDLSKNRKVHKCDTEGCDKVYTKSSHLKAHKRTHTGEKPYVCTWEGCIWRFARSD 325
            ::|....  ...::...|.|:|...||.|.|.||||||:|:||||||:|:.|.|..|..:|.|||
Human   178 AADQAPR--RRSVTPAAKRHQCPFPGCTKAYYKSSHLKSHQRTHTGERPFSCDWLDCDKKFTRSD 240

  Fly   326 ELTRHYRKHTGVKPFRCQLCTRSFSRSDHLSLHMRRH 362
            ||.||||.|||.|.|.|.||.:.|||||||:.|.|||
Human   241 ELARHYRTHTGEKRFSCPLCPKQFSRSDHLTKHARRH 277

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42741	NP_611747.2	COG5048	<273..>352	CDD:227381	44/78 (56%)
		C2H2 Zn finger	282..304	CDD:275368	13/21 (62%)
		C2H2 Zn finger	312..334	CDD:275368	13/21 (62%)
		zf-H2C2_2	326..351	CDD:463886	15/24 (63%)
		C2H2 Zn finger	342..362	CDD:275368	12/19 (63%)
KLF14	NP_619638.2	KLF14_N	2..196	CDD:409238	47/214 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	27..80		18/60 (30%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	94..116		6/24 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	142..161		7/24 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	166..195		6/30 (20%)
		COG5048	198..>283	CDD:227381	50/80 (63%)
		C2H2 Zn finger	200..219	CDD:275368	12/18 (67%)
		C2H2 Zn finger	227..249	CDD:275368	13/21 (62%)
		C2H2 Zn finger	257..277	CDD:275368	12/19 (63%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	279..323