DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG42741 and KLF6

DIOPT Version :9

Sequence 1:NP_611747.2 Gene:CG42741 / 37654 FlyBaseID:FBgn0261705 Length:362 Species:Drosophila melanogaster
Sequence 2:NP_001291.3 Gene:KLF6 / 1316 HGNCID:2235 Length:283 Species:Homo sapiens


Alignment Length:224 Identity:92/224 - (41%)
Similarity:120/224 - (53%) Gaps:41/224 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly   145 SCSYN---NGSSSGGAGSAANSMQDYE--SKFSLLSLFKNPY-KFAGGDGQASRKTSPTGGSSKP 203
            |..||   |..:|..:..:::|.::..  :||:     .:|. :.....|:.|...:.|..||..
Human    94 SFCYNLETNSLNSDVSSESSDSSEELSPTAKFT-----SDPIGEVLVSSGKLSSSVTSTPPSSPE 153

  Fly   204 LASNSSPSWKSYAGSGSPHAALNPAFGGMGRGATRKDNSSFSGINFGGGGSAFGFTTSSDSMANG 268
            |:...|..|....|.       .|:.|.:..|.:.|.....:|                |:..:|
Human   154 LSREPSQLWGCVPGE-------LPSPGKVRSGTSGKPGDKGNG----------------DASPDG 195

  Fly   269 GYNDLSKNRKVHKCDTEGCDKVYTKSSHLKAHKRTHTGEKPYVCTWEGCIWRFARSDELTRHYRK 333
                   .|:||:|...||.||||||||||||:|||||||||.|:||||.||||||||||||:||
Human   196 -------RRRVHRCHFNGCRKVYTKSSHLKAHQRTHTGEKPYRCSWEGCEWRFARSDELTRHFRK 253

  Fly   334 HTGVKPFRCQLCTRSFSRSDHLSLHMRRH 362
            |||.|||:|..|.|.|||||||:|||:||
Human   254 HTGAKPFKCSHCDRCFSRSDHLALHMKRH 282

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG42741NP_611747.2 COG5048 <273..>352 CDD:227381 57/78 (73%)
zf-C2H2 280..304 CDD:278523 17/23 (74%)
C2H2 Zn finger 282..304 CDD:275368 16/21 (76%)
zf-H2C2_2 296..>313 CDD:290200 14/16 (88%)
C2H2 Zn finger 312..334 CDD:275368 18/21 (86%)
zf-H2C2_2 326..351 CDD:290200 17/24 (71%)
C2H2 Zn finger 342..362 CDD:275368 13/19 (68%)
KLF6NP_001291.3 9aaTAD, inactive. /evidence=ECO:0000269|PubMed:31375868 62..70
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 106..198 21/126 (17%)
COG5048 177..>265 CDD:227381 58/110 (53%)
C2H2 Zn finger 205..224 CDD:275368 15/18 (83%)
C2H2 Zn finger 232..254 CDD:275368 18/21 (86%)
zf-C2H2 260..282 CDD:333835 14/21 (67%)
C2H2 Zn finger 262..282 CDD:275368 13/19 (68%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D416605at33208
OrthoFinder 1 1.000 - - FOG0000436
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR23235
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
44.020

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